Description

Rohitukine CAS NO 71294-60-5 is a chromone alkaloid of significant interest in pharmaceutical research and development. This natural compound serves as a critical intermediate and a promising lead molecule for novel therapeutic agents. It is primarily sought after by research institutions, pharmaceutical companies, and fine chemical manufacturers engaged in oncology and immunology research. Its unique biological profile makes it a valuable asset for high-value synthesis and drug discovery pipelines.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of advanced oncology drug candidates, including flavopiridol analogs.
• Biomedical Research: Used as a reference standard and active agent in studies targeting cyclin-dependent kinases (CDKs) for cancer therapy.
• Natural Product Chemistry: Serves as a purified standard for the analysis and quality control of plant extracts from Dysoxylum binectariferum and related species.
• Preclinical Development: Employed in in vitro and in vivo studies to investigate anti-inflammatory and immunomodulatory properties.
• High-Purity Fine Chemical: Supplied to laboratories and manufacturers requiring high-grade materials for sensitive chemical synthesis.

Basic Information

Product Name	Rohitukine
CAS No.	71294-60-5
Molecular Formula	C16H19NO5
Molecular Weight	305.33 g/mol
Synonyms	Rohitukine; (2R,3S,4S)-3,4-Dihydro-2-(4-hydroxy-3-methoxyphenyl)-4-(hydroxymethyl)-7-methoxy-2H-1-benzopyran-3-ol; Flavopiridol precursor; Chromone alkaloid; NSC 649890; CCG-39161
EINECS	Contact for details

Quality Control

Our Rohitukine is produced and tested under a strict quality management system to ensure batch-to-batch consistency and high purity for research applications. We provide comprehensive analytical data including HPLC purity, identity confirmation by spectroscopic methods, and impurity profiling. A Certificate of Analysis (COA) detailing all specifications and test results is supplied with each batch to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.