Description

n-4-Azido-2-Nitrophenyl-γ-Aminobutyryl-Atp is a specialized, photoactivatable ATP analog designed for cross-linking studies in biochemistry and molecular biology. This compound matters as a critical research tool for investigating ATP-binding sites, enzyme mechanisms, and protein-protein interactions through irreversible photoaffinity labeling. Researchers in pharmaceutical development, proteomics, and structural biology need this high-purity biochemical to map active sites and study energy-dependent processes with precision.

Application

• Photoaffinity Labeling: Acts as an irreversible probe for identifying and characterizing ATP-binding proteins and enzymes.
• Enzyme Mechanism Studies: Used to investigate the catalytic cycles and binding pockets of kinases, ATPases, and synthases.
• Proteomic Research: Enables the tagging and isolation of ATP-interacting proteins from complex biological mixtures for mass spectrometry analysis.
• Structural Biology: Aids in mapping ligand-binding sites within protein structures.
• Drug Discovery: Serves as a tool for target validation and screening compounds that compete for ATP-binding sites.
• Biochemical Assay Development: Utilized in creating sensitive assays to monitor ATP-dependent enzymatic activity.

Basic Information

Product Name	n-4-Azido-2-Nitrophenyl-γ-Aminobutyryl-Atp
CAS No.	71096-59-8
Molecular Formula	C₁₆H₂₂N₈O₁₃P₃
Molecular Weight	676.33 g/mol
Synonyms	4-Azido-2-nitrophenyl-γ-aminobutyryl-ATP; NAPP-ATP; γ-(4-Azido-2-nitrophenyl)aminobutyryl-ATP; 4-Azido-2-nitrophenylaminobutyryl adenosine triphosphate; Photoactivatable ATP analog; ATP-arylazide; caged ATP analog; ATP cross-linker
EINECS	Contact for details

Quality Control

Our n-4-Azido-2-Nitrophenyl-γ-Aminobutyryl-Atp is manufactured under strict quality systems to ensure high purity and batch-to-batch consistency, essential for reproducible research results. Each lot undergoes comprehensive analytical testing, including HPLC for purity and spectroscopic methods for identity confirmation. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a desiccated environment. This compound is strictly light-sensitive and hygroscopic; prolonged exposure to light, moisture, or ambient temperatures will lead to decomposition. Aliquot contents to minimize freeze-thaw cycles.

Specification

Item	Specification
Appearance	Yellow to orange solid
Identification (HPLC)	Conforms
Identification (UV-Vis)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Solubility	Soluble in aqueous buffer, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.