Description

L-Beta,γ-Dipalmitoyl-α-Phosphatidic Acid Disodium Salt is a high-purity, synthetic phospholipid derivative, specifically the disodium salt of phosphatidic acid with defined palmitoyl chains. This compound serves as a critical building block and model lipid in advanced research and formulation development, offering superior consistency and defined structure compared to natural extracts. It is essential for pharmaceutical, cosmetic, and biochemical research applications where precise lipid composition and purity are paramount for reproducible results.

Application

• Liposome and Nanoparticle Formulation: A key anionic phospholipid component for creating stable, charged liposomal drug delivery systems and lipid nanoparticles (LNPs) for mRNA/cargo encapsulation.
• Biochemical Research & Cell Signaling Studies: Used as a substrate or standard in enzymatic assays (e.g., phospholipase studies) and to investigate the role of phosphatidic acid in cellular signal transduction pathways.
• Model Membrane Systems: Incorporated into artificial lipid bilayers and vesicles to study membrane biophysics, protein-lipid interactions, and membrane permeability.
• Cosmetic Actives & Skin Care: Employed in high-end cosmetic formulations for its emulsifying properties and potential role in skin barrier function and delivery of active ingredients.
• Pharmaceutical Excipient: Functions as a solubilizing agent, emulsifier, or component in complex drug formulations to enhance stability and bioavailability.
• Reference Standard: Serves as a high-purity analytical standard for quality control and quantification of phosphatidic acid species in various matrices using techniques like HPLC and LC-MS.

Basic Information

Product Name	L-Beta,γ-Dipalmitoyl-α-Phosphatidic Acid Disodium Salt
CAS No.	71065-87-7
Molecular Formula	C35H66Na2O8P
Molecular Weight	706.84 g/mol
Synonyms	1,2-Dipalmitoyl-sn-glycero-3-phosphate disodium salt; PA(16:0/16:0) disodium salt; Phosphatidic Acid (dipalmitoyl) disodium salt; DPPA disodium salt; 1,2-Dihexadecanoyl-sn-glycerol-3-phosphate disodium salt; sn-Glycero-3-phosphoric acid 1,2-dipalmitoyl ester disodium salt; L-α-Phosphatidic acid, dipalmitoyl-, disodium salt
EINECS	Contact for details

Quality Control

Our L-Beta,γ-Dipalmitoyl-α-Phosphatidic Acid Disodium Salt is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity suitable for research and formulation. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to relevant cGMP guidelines for the production of critical raw materials, and our quality protocols are designed to meet the stringent requirements of pharmaceutical and advanced material applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant for long-term stability. This product is hygroscopic (moisture-sensitive). Allow the sealed container to equilibrate to room temperature before opening to minimize moisture condensation. For short-term use, store in a cool, dry place (2-8°C).

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Purity (TLC)	Single major spot
Solubility	Soluble in chloroform, methanol; forms dispersions in water
Water Content (KF)	≤ 3.0%
Residue on Ignition	≤ 2.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.