Description

(±)-5-Hete, (±)-(6E,8Z,11Z,14Z)-5-Hydroxyeicosatetraenoic Acid Solution is a high-purity, synthetic eicosanoid derivative, specifically a 5-hydroxyeicosatetraenoic acid (5-HETE) isomer. This compound is a critical biochemical intermediate and research standard for studying the lipoxygenase pathway and its role in inflammatory and immune responses. It is essential for researchers and developers in pharmaceutical discovery, biochemical research, and analytical method development, providing a reliable reference material for in vitro studies and assay calibration.

Application

• Biochemical Research Standard: Used as a primary reference standard for the quantification and identification of 5-HETE and related eicosanoids in biological samples via LC-MS/MS or HPLC.
• Inflammation & Immunology Studies: A key tool for investigating the mechanisms of the 5-lipoxygenase (5-LOX) pathway, leukotriene biosynthesis, and associated inflammatory processes.
• Pharmaceutical Development: Serves as a critical intermediate or reference compound in the R&D of novel anti-inflammatory drugs and lipoxygenase pathway inhibitors.
• Cell Signaling Research: Applied in cell culture studies to elucidate the role of hydroxyeicosatetraenoic acids (HETEs) in cellular signaling, proliferation, and apoptosis.
• Analytical Method Validation: Essential for developing, validating, and calibrating analytical methods in clinical research and diagnostic assay development.

Basic Information

Item	Detail
Product Name	(±)-5-Hete, (±)-(6E,8Z,11Z,14Z)-5-Hydroxyeicosatetraenoic Acid Solution
CAS No.	71030-39-2
Molecular Formula	C₂₀H₃₂O₃
Molecular Weight	320.47 g/mol
Synonyms	(±)-5-HETE; 5-Hydroxyeicosatetraenoic Acid; (6E,8Z,11Z,14Z)-5-Hydroxyicosa-6,8,11,14-tetraenoic Acid; 5(S)-HETE; rac-5-HETE; 5-Lipoxygenase Metabolite; Arachidonic Acid 5-Lipoxygenase Metabolite; 5-Hydroxy-6E,8Z,11Z,14Z-eicosatetraenoic Acid
EINECS	Contact for details

Quality Control

Our (±)-5-HETE Solution is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC purity analysis and identity confirmation (IR, NMR), to ensure high chemical and isomeric purity suitable for sensitive research applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere. The solution is easily oxidized (store under inert atmosphere) and light-sensitive. Allow the product to equilibrate to room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow solution
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95% (Area Percent)
Isomeric Purity (HPLC)	Specified on COA
Solvent	Ethanol or other specified solvent
Concentration	Typically 1 mg/mL or as specified

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.