Description

Asialoganglioside-Gm1 is a key biochemical derivative of the monosialoganglioside GM1, where the terminal sialic acid residue has been removed. This modification makes it a critical tool for studying ganglioside function, cell signaling, and receptor interactions in neurological research. It is primarily utilized by research institutions and pharmaceutical developers focused on neuroscience, lipid biochemistry, and glycobiology. The compound is supplied to the global market with a focus on high purity and batch-to-batch consistency for reliable experimental results.

Application

• Neuroscience Research: Used as a standard or inhibitor in studies of ganglioside metabolism, neuronal differentiation, and synaptic function.
• Biochemical Assays: Serves as a substrate or ligand in enzymatic assays and binding studies to investigate specific glycosidase activities.
• Cell Biology Studies: Employed to explore its role in cell membrane dynamics, lipid raft composition, and signal transduction pathways.
• Pharmaceutical Development: Acts as a reference compound or intermediate in the research and development of therapies targeting neurological disorders.
• Glycobiology Research: Essential for investigating the structure and function of complex carbohydrates and their role in cellular recognition.

Basic Information

Item	Details
Product Name	Asialoganglioside-Gm1
CAS No.	71012-19-6
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Asialo-GM1; GM1a; Ganglioside GA1; Asialo Monosialoganglioside GM1; β-Gal-(1->3)-β-GalNAc-(1->4)-[α-Neu5Ac-(2->3)]-β-Gal-(1->4)-β-Glc-(1<->1')-Ceramide (desialylated); GA1 Ganglioside; II3-α-Neu5Ac-GgOse4Cer (asialo derivative)
EINECS	Contact for details

Quality Control

Our Asialoganglioside-Gm1 is produced under stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including chromatographic purity analysis and identity confirmation, to ensure it meets the high standards required for research applications. A Certificate of Analysis (COA) detailing specific results for purity, identity, and other critical parameters is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. Allow the vial to reach room temperature in a desiccator before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/IR)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Loss on Drying	≤ 5.0 %
Solubility	Soluble in chloroform/methanol mixtures

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.