Description

Suc-Ala-Ala-Pro-Phe-Pna is a chromogenic peptide substrate specifically designed for the assay of chymotrypsin and related serine proteases. This compound matters for researchers and quality control laboratories requiring precise, spectrophotometric measurement of enzymatic activity. It is primarily needed by the pharmaceutical, biotechnology, and diagnostic industries for enzyme kinetics studies, inhibitor screening, and purity testing of proteolytic enzymes.

Application

• Enzyme Activity Assays: Primary substrate for the quantitative determination of α-chymotrypsin activity.
• Inhibitor Screening: Used in high-throughput screening (HTS) platforms to identify and characterize novel chymotrypsin inhibitors for drug discovery.
• Biochemical Research: Essential tool for studying enzyme kinetics, mechanism of action, and substrate specificity of serine proteases.
• Quality Control: Employed in the pharmaceutical industry to test the potency and consistency of enzyme-based active pharmaceutical ingredients (APIs).
• Diagnostic Development: Serves as a key component in developing clinical diagnostic kits that measure protease levels.

Basic Information

Product Name	Suc-Ala-Ala-Pro-Phe-Pna
CAS No.	70967-97-4
Molecular Formula	C30H37N7O9
Molecular Weight	639.66 g/mol
Synonyms	Suc-AAPF-pNA; N-Succinyl-Ala-Ala-Pro-Phe p-nitroanilide; Suc-AAPF-pNA; N-Succinyl-Alanyl-Alanyl-Prolyl-Phenylalanyl p-Nitroanilide; Chymotrypsin Substrate I; Suc-AAPF-PNA; Suc-Ala-Ala-Pro-Phe-pNA; Suc-AAPF-pNA Substrate
EINECS	Contact for details

Quality Control

Our Suc-Ala-Ala-Pro-Phe-Pna is manufactured under strict quality systems to ensure high purity and batch-to-batch consistency for reliable research and industrial applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and performance in standard enzymatic assays. We adhere to relevant quality guidelines to support our global customer base in pharmaceutical development and life science research.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive) and light-sensitive; prolonged exposure to ambient conditions or light may affect stability and performance.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in DMSO, DMF
Functional Activity	Suitable for chymotrypsin assay

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.