Description

1-Palmitoyl-2-Arachidonoyl-Sn-Glycero-3-Phosphoethanolamine is a high-purity, synthetic phospholipid belonging to the phosphatidylethanolamine (PE) class, specifically a mixed-acid species with defined acyl chains. This compound is a critical biochemical tool and a key component for studying and modulating membrane structure, lipid signaling pathways, and cellular processes. It is essential for researchers and manufacturers in lipidomics, pharmaceutical development, and advanced biomembrane research, where precise lipid composition is paramount for reproducibility and biological activity.

Application

• Biomembrane Research & Model Systems: Used to create defined lipid bilayers, liposomes, and supported membranes for studying membrane fluidity, protein-lipid interactions, and fusion events.
• Lipidomics & Analytical Standards: Serves as a critical reference standard for the identification and quantification of phosphatidylethanolamine species in mass spectrometry-based lipidomic profiling.
• Drug Delivery Systems: Incorporated into liposomal formulations to influence membrane stability, targeting, and payload release characteristics.
• Cell Signaling Studies: Utilized to investigate the role of specific phospholipids in intracellular signaling cascades, particularly those involving arachidonic acid-derived mediators.
• Biochemical Reagent: Acts as a substrate or co-factor for enzymes like phospholipases or in assays studying lipid metabolism and transport.
• Pharmaceutical Excipient Development: Explored for its potential as a biocompatible component in advanced therapeutic formulations.

Basic Information

Item	Detail
Product Name	1-Palmitoyl-2-Arachidonoyl-Sn-Glycero-3-Phosphoethanolamine
CAS No.	70812-59-8
Molecular Formula	C41H74NO8P
Molecular Weight	740.00 g/mol
Synonyms	PAPC; 1-Palmitoyl-2-arachidonoyl-phosphatidylethanolamine; PE(16:0/20:4); (2R)-2,3-Bis[[(Z)-hexadec-9-enoyl]oxy]propyl 2-(trimethylazaniumyl)ethyl phosphate; 1-Hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphoethanolamine; L-α-Phosphatidylethanolamine, 1-palmitoyl-2-arachidonoyl-; Arachidonoyl Palmitoyl Phosphatidylethanolamine
EINECS	Contact for details

Quality Control

Our 1-Palmitoyl-2-Arachidonoyl-Sn-Glycero-3-Phosphoethanolamine is produced under stringent conditions to ensure batch-to-batch consistency and high chemical purity, suitable for sensitive research applications. Quality is verified through a comprehensive suite of analytical techniques including NMR, HPLC, and mass spectrometry. A detailed Certificate of Analysis (COA) is provided with each batch, confirming identity, purity, and critical specifications.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen). The product is hygroscopic (moisture-sensitive) and easily oxidized; allow the sealed vial to equilibrate to room temperature before opening to minimize condensation and exposure to air.

Specification

Item	Specification
Appearance	White to off-white solid or waxy solid
Identification (NMR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Solubility	Soluble in chloroform, ethanol; slightly soluble in aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.