Description

1-Palmitoyl-2-Pyrenedecanoylphosphatidylcholine is a synthetic, fluorescently labeled phospholipid, a critical tool for advanced biophysical and membrane research. Its core value lies in the pyrene fluorophore, which enables sensitive detection and analysis of membrane dynamics, fusion, and lipid-protein interactions. This compound is essential for researchers and developers in academic institutions, pharmaceutical R&D, and biotechnology companies focused on lipidomics, drug delivery systems, and model membrane studies.

Application

• Membrane Fluidity and Dynamics Studies: As a fluorescent probe to investigate phase transitions, lateral diffusion, and lipid packing in artificial and cellular membranes.
• Liposome and Drug Delivery Research: Used to label and track liposomes, enabling the study of cellular uptake, stability, and fusion kinetics of nano-carriers.
• Lipid-Protein Interaction Analysis: Employed in assays to monitor the binding and effect of proteins, peptides, or drugs on membrane structure.
• Model Membrane Assembly: A key component in constructing defined lipid bilayers (e.g., supported lipid bilayers, giant unilamellar vesicles) for controlled experiments.
• Enzymatic Activity Assays: Serving as a substrate for phospholipases or other lipid-modifying enzymes, with activity measured via fluorescence change.
• High-Throughput Screening (HTS): Utilized in fluorescence-based assays to discover new therapeutic compounds that target membrane-related processes.

Basic Information

Product Name	1-Palmitoyl-2-Pyrenedecanoylphosphatidylcholine
CAS No.	70700-33-3
Molecular Formula	C₅₅H₈₆NO₈P
Molecular Weight	928.24 g/mol
Synonyms	Pyrene-PC; 1-Palmitoyl-2-(10-pyrenyldecanoyl)-sn-glycero-3-phosphocholine; 16:0-10:0 Pyrene PC; β-Py-C10-HPC; Fluorescent Phosphatidylcholine; Pyrene-labeled PC; 2-(10-Pyrenyldecanoyl)-1-hexadecanoyl-sn-glycero-3-phosphocholine
EINECS	Contact for details

Quality Control

Our 1-Palmitoyl-2-Pyrenedecanoylphosphatidylcholine is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity, suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and fluorescence properties. We adhere to ISO 9001 standards, and our quality systems support traceability for all materials.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to ensure long-term stability. This product is hygroscopic (moisture-sensitive) and strictly light-sensitive; protect from all light exposure during handling and storage. Allow the sealed vial to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	Yellow to orange solid or film
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 98%
Pyrene Content (Fluorimetry)	Conforms to theoretical
Solubility	Soluble in chloroform, DMSO; forms micelles in aqueous buffer
Fluorescence Properties	Excitation ~342 nm, Emission ~376 nm (monomer)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.