Description

Catharanthine Sulfate is a significant alkaloid salt derived from the Madagascar periwinkle plant, *Catharanthus roseus*. This compound serves as a crucial intermediate in the synthesis of complex bisindole alkaloids, most notably the anticancer agents vinblastine and vincristine. It is primarily utilized by pharmaceutical research organizations, fine chemical manufacturers, and academic institutions engaged in oncology drug discovery and development. The sulfate salt form offers enhanced stability and solubility for specific synthetic and formulation applications.

Application

• Pharmaceutical Intermediate: Key precursor in the semi-synthetic production of vital anticancer drugs, including vinblastine and vincristine.
• Biochemical Research: Used as a reference standard and active agent in studies investigating the biosynthesis, mechanism of action, and structure-activity relationships of *Catharanthus* alkaloids.
• Fine Chemical Synthesis: Employed as a building block for the chemical modification and creation of novel indole alkaloid derivatives with potential therapeutic activity.
• Academic & Contract Research: Essential material for universities and CROs (Contract Research Organizations) conducting pharmacological and phytochemical research.
• Analytical Standard: Serves as a high-purity certified reference material (CRM) for quality control and analytical method development in pharmaceutical laboratories.

Basic Information

Product Name	Catharanthine Sulfate
CAS No.	70674-90-7
Molecular Formula	C₂₁H₂₄N₂O₂ · H₂SO₄
Molecular Weight	440.50 g/mol
Synonyms	Catharanthine sulfate salt; (19S)-19-Hydroxy-1-methylandrosta-1,4-diene-3,17-dione sulfate; Catharanthine hemisulfate; Vincamedine sulfate; Catharanthine sulphate; Perivine sulfate (related); Akuammicine derivative sulfate
EINECS	Contact for details

Quality Control

Our Catharanthine Sulfate is produced and tested under a strict quality management system. Each batch undergoes comprehensive analysis to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical intermediate and research-grade materials. A detailed Certificate of Analysis (COA) providing results for assay, related substances, residual solvents, and other critical parameters is supplied with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a dry environment and away from direct light exposure to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.