Description

(17R,19E)-19,20-Didehydro-1-Demethylajmalan-10,17-Diol is a high-purity, structurally defined alkaloid derivative. This compound is of significant interest in advanced pharmaceutical research and development, particularly for its role as a key synthetic intermediate or reference standard. It is primarily utilized by research institutions and pharmaceutical companies engaged in the synthesis of complex natural products and the development of novel therapeutic agents. The precise stereochemistry and functional groups make it a valuable building block for medicinal chemistry programs.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of complex indole alkaloids and potential active pharmaceutical ingredients (APIs).
• Reference Standard: Used as a high-purity analytical standard for quality control, method development, and identification in pharmaceutical analysis.
• Medicinal Chemistry Research: Employed as a scaffold for structure-activity relationship (SAR) studies to explore new biological activities.
• Biochemical Research: Utilized in studies investigating alkaloid biosynthesis pathways and enzyme mechanisms.
• Academic Research: Applied in organic chemistry laboratories for teaching and research on complex molecule synthesis and stereochemistry.

Basic Information

Item	Details
Product Name	(17R,19E)-19,20-Didehydro-1-Demethylajmalan-10,17-Diol
CAS No.	70509-79-4
Molecular Formula	C20H24N2O2
Molecular Weight	324.42 g/mol
Synonyms	1-Demethyl-19,20-didehydroajmalan-10,17-diol; 10,17-Dihydroxy-1-demethyl-19,20-didehydroajmalan; Ajmalan-10,17-diol, 1-demethyl-19,20-didehydro-, (17R,19E)-; (17R,19E)-19,20-Didehydro-1-demethylajmalan-10,17-diol; 1-Norajmaline derivative
EINECS	Contact for details

Quality Control

Our (17R,19E)-19,20-Didehydro-1-Demethylajmalan-10,17-Diol is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and chiral analysis to verify stereochemical integrity. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with research-grade specifications. Our quality systems are designed to meet the stringent requirements of pharmaceutical R&D and analytical laboratories.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.