Description

1,2-Hexanoylthiophosphotidylcholine is a specialized synthetic phospholipid derivative, distinguished by its hexanoyl and thio-modified phosphate groups. This compound is valued for its unique physicochemical properties, making it a critical intermediate in advanced research and formulation development. It is primarily sought after by researchers and product developers in the pharmaceutical, biotechnology, and advanced material science sectors for applications requiring tailored lipid behavior and membrane interactions.

Application

• Lipid Nanoparticle (LNP) Research: A key component in the development and optimization of novel LNP formulations for drug and gene delivery systems.
• Biomembrane Studies: Used as a synthetic analog to study membrane fluidity, permeability, and the function of membrane-associated proteins.
• Pharmaceutical Excipient Development: Serves as a functional excipient in the design of liposomal and other colloidal drug carriers to enhance stability and targeting.
• Bioconjugation & Probe Synthesis: Acts as a versatile building block for the synthesis of fluorescent or tagged phospholipids used in cellular imaging and diagnostics.
• Cosmetic & Dermal Formulations: Incorporated into high-end cosmetic products for its emulsifying properties and potential skin barrier enhancement effects.
• Biochemical Reagent: Utilized in enzymatic assays and studies involving phospholipases and other lipid-metabolizing enzymes.

Basic Information

Product Name	1,2-Hexanoylthiophosphotidylcholine
CAS No.	70504-26-6
Molecular Formula	C14H30NO6PS
Molecular Weight	371.42 g/mol
Synonyms	1,2-Dihexanoyl-sn-glycero-3-thiophosphocholine; Hexanoyl Thiophosphatidylcholine; 1,2-Dihexanoylthiophosphatidylcholine; Thiophosphatidylcholine, 1,2-dihexanoyl; sn-Glycero-3-phosphothiocholine, 1,2-dihexanoate; L-α-1,2-Dihexanoylthiophosphatidylcholine; 3-sn-Phosphatidylthiocholine, 1,2-dihexanoyl; PC(6:0/6:0) thiophosphate analog
EINECS	Contact for details

Quality Control

Our 1,2-Hexanoylthiophosphotidylcholine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) due to its hygroscopic and light-sensitive nature. For long-term storage, desiccants are recommended. Allow the sealed container to equilibrate to room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid or waxy solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0%
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.