Description

(-)-Petasinecine CAS NO 70494-70-1 is a specific enantiomer of the pyrrolizidine alkaloid petasinecine, a key structural component found in plants of the *Petasites* genus. This compound is of significant interest in phytochemical research and natural product synthesis due to its unique stereochemistry and biological precursor role. It serves as a critical intermediate and reference standard for researchers and manufacturers in the pharmaceutical, nutraceutical, and botanical extract industries.

Application

• Pharmaceutical Reference Standard: Used as a high-purity certified standard for the identification, assay, and impurity profiling of pyrrolizidine alkaloid-containing products.
• Natural Product Research: A vital intermediate in the study of the biosynthesis, metabolism, and toxicology of pyrrolizidine alkaloids in medicinal plants.
• Organic Synthesis: Serves as a chiral building block or starting material for the synthesis of more complex natural products and novel chemical entities.
• Analytical Chemistry: Employed in method development and validation for chromatographic (HPLC, LC-MS) techniques aimed at detecting and quantifying pyrrolizidine alkaloids.
• Botanical Extract Quality Control: Used to calibrate systems and ensure the safety profile of herbal supplements by monitoring for specific alkaloid content.
• Toxicological Studies: Acts as a precise chemical agent in research investigating the hepatotoxic and genotoxic effects of pyrrolizidine alkaloids.

Basic Information

Product Name	(-)-Petasinecine
CAS No.	70494-70-1
Molecular Formula	C8H13NO2
Molecular Weight	155.19 g/mol
Synonyms	(1R,2R,7aR)-1,2-Dihydroxy-1,2,3,5,6,7a-hexahydro-7H-pyrrolizin-7-one; (-)-Petasinecine; (7aR)-Petasinecine; L-Petasinecine; Petasinecine enantiomer; 1,2-Dihydroxypyrrolizidine derivative
EINECS	Contact for details

Quality Control

Our (-)-Petasinecine is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis to confirm enantiomeric excess, and spectroscopic identification (IR, NMR, MS). We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with research-grade specifications. Our quality commitment supports reliable and reproducible results for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. For long-term storage, consider keeping the material under inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.