Description

5H-Benzo[G]-1,3-Benzodioxolo[6,5,4-De]Quinolin-12-Ol, 6,7,7A,8-Tetrahydro-10-Methoxy-, (7Ar)- is a complex heterocyclic organic compound of significant interest in advanced chemical synthesis. This compound matters as a sophisticated chemical intermediate or reference standard for research into novel pharmacologically active molecules, particularly within the alkaloid family. It is primarily needed by pharmaceutical R&D laboratories, academic research institutions, and specialty chemical manufacturers focused on developing new therapeutic agents or studying complex natural product analogs.

Application

• Pharmaceutical Research & Development: Serves as a key intermediate or building block in the synthesis of novel alkaloid-based drug candidates.
• Reference Standard Material: Used as a high-purity analytical standard for method development, quality control, and identification in research settings.
• Medicinal Chemistry Studies: Employed in structure-activity relationship (SAR) studies to explore and optimize biological activity profiles.
• Natural Product Synthesis: Acts as a synthetic target or intermediate in the total synthesis of complex natural products containing the benzodioxoloquinoline scaffold.
• Biochemical Research: Potential use as a tool compound for investigating specific biological pathways or enzyme interactions in vitro.
• Specialty Chemical Manufacturing: Utilized in the production of high-value, low-volume fine chemicals for advanced applications.

Basic Information

Product Name	5H-Benzo[G]-1,3-Benzodioxolo[6,5,4-De]Quinolin-12-Ol, 6,7,7A,8-Tetrahydro-10-Methoxy-, (7Ar)-
CAS No.	70420-58-5
Molecular Formula	C19H17NO4
Molecular Weight	323.34 g/mol
Synonyms	(7aR)-6,7,7a,8-Tetrahydro-10-methoxy-5H-benzo[g][1,3]benzodioxolo[6,5,4-de]quinolin-12-ol; 10-Methoxy-6,7,7a,8-tetrahydro-5H-benzo[g][1,3]benzodioxolo[6,5,4-de]quinolin-12-ol (7aR)-; Berberrubine (common name for related structure); 12-Hydroxy-10-methoxy-5,6,7,8-tetrahydro[1,3]dioxolo[4,5-g]isoquinolino[3,2-a]isoquinoline; Aporphine alkaloid derivative
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We provide comprehensive analytical data to support research and development needs. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request. Production can be aligned with cGMP guidelines for advanced pharmaceutical applications upon requirement.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.