Description

Isotetrandrine n-2'-Oxide is a specific, high-purity alkaloid derivative of tetrandrine, a bisbenzylisoquinoline compound. This product matters for researchers and manufacturers requiring a precisely defined chemical entity for pharmacological studies and advanced development. It is primarily needed by the pharmaceutical, biotechnology, and academic research sectors for applications in drug discovery and biochemical research.

Application

• Pharmaceutical Research & Development: Serves as a key reference standard and intermediate in the investigation of anti-inflammatory, anti-cancer, and calcium channel blocking agents.
• Biochemical Assay Development: Used as a precise tool compound to study cellular pathways and receptor interactions in vitro.
• Natural Product Chemistry: Acts as a critical analytical standard for the identification, quantification, and quality control of tetrandrine and related alkaloids in botanical extracts.
• Academic & Institutional Research: Employed in university and government labs for fundamental studies on the structure-activity relationships of isoquinoline alkaloids.
• Preclinical Studies: Utilized in animal model research to evaluate pharmacokinetics, metabolism, and efficacy of novel therapeutic candidates.

Basic Information

Product Name	Isotetrandrine n-2'-Oxide
CAS No.	70191-83-2
Molecular Formula	C38H42N2O7
Molecular Weight	638.75 g/mol
Synonyms	Isotetrandrine N-2'-Oxide; Isotetrandrine N-2'-Oxide; Isotetrandrine N-Oxide; Isotetrandrine Oxide; (1S)-6,6',7,12-Tetramethoxy-2,2'-dimethyl-1-[(1S)-1,2,3,4-tetrahydro-6-methoxy-1-isoquinolinylmethyl]-2,2'-(1,4-butanediyl)bis[1H-isoquinolin-2-ium-2-olate]; Tetrandrine derivative; Bisbenzylisoquinoline alkaloid N-oxide.
EINECS	Contact for details

Quality Control

Our Isotetrandrine n-2'-Oxide is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (IR, NMR, MS). We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.