Description

Dopamine, [7-3H(N)] CAS NO 70097-41-5 is a high-specific-activity tritium-labeled form of the essential neurotransmitter and hormone dopamine. This radiochemical is critical for advanced research requiring precise detection and quantification of dopamine pathways, receptor binding, and metabolic studies. It is primarily utilized by pharmaceutical R&D teams, neurobiology research laboratories, and clinical diagnostic developers for tracer studies, autoradiography, and competitive binding assays.

Application

• Neuropharmacology Research: Used as a tracer to study dopamine receptor (D1, D2, etc.) density, distribution, and binding affinity in vitro and ex vivo.
• Neurotransmitter Uptake & Metabolism Studies: Tracks the kinetics of dopamine reuptake by dopamine transporters (DAT) and its enzymatic breakdown.
• Drug Discovery & Development: Enables high-throughput screening and mechanistic studies for novel antipsychotics, antidepressants, and Parkinson's disease therapeutics.
• Autoradiography & Imaging: Facilitates the visualization and mapping of dopaminergic pathways and receptor sites in tissue sections.
• Clinical Research Assays: Employed in developing and validating diagnostic assays for neurological and psychiatric disorders.
• Biochemical Pathway Analysis: Investigates the synthesis, storage, release, and degradation of dopamine in cellular models.

Basic Information

Product Name	Dopamine, [7-3H(N)]
CAS No.	70097-41-5
Molecular Formula	C8H11NO2 (³H-labeled)
Molecular Weight	~153.18 g/mol (varies with specific activity)
Synonyms	4-(2-Aminoethyl)benzene-1,2-diol, [7-³H]; 3,4-Dihydroxyphenethylamine-7-³H; 2-(3,4-Dihydroxyphenyl)ethylamine-7-³H; Hydroxytyramine-7-³H; DA-7-³H; Tritiated Dopamine; [³H]Dopamine; Intropin (labeled)
EINECS	Contact for details

Quality Control

Every batch of Dopamine, [7-3H(N)] is manufactured and analyzed under strict quality systems to ensure radiochemical purity, specific activity, and chemical stability. Our quality commitment includes verification of identity and purity via advanced chromatographic techniques. A comprehensive Certificate of Analysis (COA), detailing specific activity (Ci/mmol or GBq/mmol), radiochemical purity, solvent composition, and analytical methods, is provided with each shipment to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store frozen (-20°C or below) in the original solvent as supplied. Due to its highly volatile nature (tritium), appropriate containment and laboratory practices for handling radiochemicals must be followed at all times. For long-term stability, avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	Clear, colorless to slightly yellow solution
Identification (HPLC/Co-injection)	Conforms to reference standard
Specific Activity	20-40 Ci/mmol (740-1480 GBq/mmol) [Custom ranges available]
Radiochemical Purity (HPLC)	≥ 97%
Chemical Purity (HPLC)	≥ 95%
Solvent	Ethanol: Water (with stabilizer) or custom
Concentration	1 mCi/mL (37 MBq/mL) [Custom concentrations available]

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.