Description

1,3,12-Trihydroxycholanoic Acid is a hydroxylated bile acid derivative, a key intermediate in the synthesis of more complex steroidal compounds. Its multi-hydroxyl structure provides unique chemical functionality, making it valuable for research and development in pharmaceutical chemistry. This compound is primarily sought by manufacturers and researchers in the pharmaceutical, biotechnology, and fine chemical sectors for its role in developing therapeutic agents and biochemical tools.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel steroidal drugs and therapeutic agents targeting metabolic and liver-related pathways.
• Biochemical Research: Used as a reference standard or substrate in studies of bile acid metabolism, liver function, and related enzymatic processes.
• Fine Chemical Synthesis: Serves as a chiral starting material or intermediate in the multi-step synthesis of complex organic molecules for high-value applications.
• Metabolic Pathway Studies: Employed in laboratory research to investigate the biosynthesis and catabolism of bile acids and other sterols.
• Diagnostic Reagent Development: Potential use in formulating calibrators or components for diagnostic kits related to liver and digestive health.

Basic Information

Product Name	1,3,12-Trihydroxycholanoic Acid
CAS No.	70050-65-6
Molecular Formula	C₂₄H₄₀O₅
Molecular Weight	408.57 g/mol
Synonyms	3α,7α,12α-Trihydroxy-5β-cholan-24-oic Acid; 3α,7α,12α-Trihydroxy-5β-cholanoic Acid; 1,3,12-Trihydroxy-5β-cholan-24-oic Acid; Trihydroxycholanoic Acid; 5β-Cholan-24-oic acid-3α,7α,12α-triol; Hyocholic Acid (Note: Hyocholic acid typically refers to the 3α,6α,7α-trihydroxy isomer; this is the 3α,7α,12α isomer).
EINECS	Contact for details

Quality Control

Our 1,3,12-Trihydroxycholanoic Acid is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including identity confirmation, purity assay, and impurity profiling, to ensure it meets the stringent requirements for research and synthesis. Certificates of Analysis (COA) detailing all test results are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent absorption of atmospheric moisture, which may affect stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.