Description

Ethyl-Coenzyme A is a specialized biochemical reagent and a key derivative of the essential metabolic cofactor Coenzyme A. This compound is primarily utilized as a critical substrate and inhibitor in enzymatic studies to elucidate metabolic pathways, particularly those involving fatty acid metabolism and acetylation reactions. It is essential for research and development laboratories in the pharmaceutical, biotechnology, and life science sectors focused on metabolic engineering, drug discovery, and biochemical assay development.

Application

• Enzymology Research: Serves as a specific substrate or competitive inhibitor for studying acyltransferase and synthetase enzymes.
• Metabolic Pathway Analysis: Used in vitro to investigate and map fatty acid elongation, oxidation, and lipid biosynthesis cycles.
• Pharmaceutical Development: Employed in high-throughput screening assays to identify potential drug candidates targeting metabolic disorders.
• Biochemical Reagent: A key component in diagnostic kits and research-grade reagents for measuring specific enzyme activities.
• Academic Research: Fundamental tool for university and institutional labs conducting basic research on cellular metabolism and bioenergetics.
• Biocatalysis & Synthetic Biology: Used as a building block in engineered enzymatic systems for the production of fine chemicals or novel compounds.

Basic Information

Product Name	Ethyl-Coenzyme A
CAS No.	70019-68-0
Molecular Formula	C23H38N7O17P3S
Molecular Weight	833.55 g/mol
Synonyms	Ethyl-CoA; S-Ethyl-coenzyme A; Coenzyme A, S-ethyl-; Acetyl-CoA analogue; Ethyl thioester of CoA; 3'-Phosphoadenosine 5'-(3-[(3R)-3-hydroxy-2,2-dimethyl-4-oxo-4-{[3-oxo-3-({2-[(ethylsulfanyl)-carbonyl]amino}ethyl)amino]propyl}butyl] hydrogen diphosphate); Adenosine 5'-(trihydrogen diphosphate), 3-(3-hydroxy-2,2-dimethyl-4-oxo-4-{[3-oxo-3-({2-[(ethylthio)carbonyl]amino}ethyl)amino]propyl}butyl) ester, (R)-
EINECS	Contact for details

Quality Control

Our Ethyl-Coenzyme A is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification and identity confirmation by spectroscopic methods, to ensure it meets the exacting standards required for research applications. A Certificate of Analysis (COA) detailing purity, assay results, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term stability, store desiccated. Allow the vial to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder or lyophilized solid
Identification (HPLC/UV)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Assay (Enzymatic)	≥ 90% (by acetyltransferase assay)
Water Content (KF)	≤ 5.0 %
Solubility	Soluble in water, buffer solutions

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.