Description

9-Fluoro-11Beta,17-Dihydroxy-16Alpha-Methyl-3,20-Dioxopregna-1,4-Dien-21-Yl 2-[2-(2-Ethoxyethoxy)Ethoxy]Acetate is a high-purity synthetic corticosteroid derivative, recognized for its potent anti-inflammatory and immunosuppressive activity. This compound is of critical importance in advanced pharmaceutical research and development, serving as a key intermediate or active pharmaceutical ingredient (API) for novel therapeutic formulations. It is primarily needed by pharmaceutical manufacturers, R&D laboratories, and fine chemical suppliers targeting the development of topical and systemic corticosteroid treatments.

Application

• Key intermediate in the synthesis of advanced topical corticosteroid pharmaceuticals.
• Active Pharmaceutical Ingredient (API) for anti-inflammatory and immunosuppressant drug formulations.
• Critical material for pharmaceutical R&D in dermatology, ophthalmology, and respiratory medicine.
• Reference standard for analytical method development and quality control in pharmaceutical manufacturing.
• Building block for creating novel prodrugs with enhanced bioavailability profiles.
• Research chemical for studying glucocorticoid receptor mechanisms and signaling pathways.

Basic Information

Product Name	9-Fluoro-11Beta,17-Dihydroxy-16Alpha-Methyl-3,20-Dioxopregna-1,4-Dien-21-Yl 2-[2-(2-Ethoxyethoxy)Ethoxy]Acetate
CAS No.	7743-96-6
Molecular Formula	C30H43FO9
Molecular Weight	566.66 g/mol
Synonyms	Flumethasone Pivalate (common pharmaceutical name); Flumethasone 21-(3,6,9-Trioxaundecanoate); Flumethasone 21-[2-[2-(2-Ethoxyethoxy)ethoxy]acetate]; SQ 15102; 9α-Fluoro-11β,17α,21-trihydroxy-16α-methylpregna-1,4-diene-3,20-dione 21-[2-[2-(2-ethoxyethoxy)ethoxy]acetate]; Flumetasone Pivalate (alternate spelling); Flumethasone Trimethylacetate (related compound name); Locorten (associated brand/trade name).
EINECS	Contact for details

Quality Control

Our 9-Fluoro-11Beta,17-Dihydroxy-16Alpha-Methyl-3,20-Dioxopregna-1,4-Dien-21-Yl 2-[2-(2-Ethoxyethoxy)Ethoxy]Acetate is manufactured under strict quality systems suitable for pharmaceutical applications. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting high standards for pharmaceutical intermediates and APIs. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are provided for every shipment to support your regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.