Description

(3β,16E,20β)-16,17-Didehydro-17-Methoxycorynan-16-Carboxylic Acid Methyl Ester is a high-purity, structurally defined indole alkaloid derivative of significant interest in advanced organic synthesis and pharmaceutical research. This compound serves as a critical synthetic intermediate and reference standard for developing novel bioactive molecules. It is primarily utilized by research institutions, pharmaceutical development laboratories, and fine chemical manufacturers focused on alkaloid chemistry, medicinal chemistry, and process development.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex indole alkaloids and potential active pharmaceutical ingredients (APIs).
• Reference Standard: Used for analytical method development, validation, and quality control in research and manufacturing settings.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies to explore new therapeutic agents.
• Process Chemistry: Serves as a starting material or intermediate in scaling up synthetic routes for target molecules.
• Academic Research: Utilized in universities and institutes for studies in natural product synthesis and alkaloid chemistry.
• Biochemical Research: Potential use as a probe or ligand in studying biological pathways and enzyme interactions.

Basic Information

Product Name	(3β,16E,20β)-16,17-Didehydro-17-Methoxycorynan-16-Carboxylic Acid Methyl Ester
CAS No.	7729-22-8
Molecular Formula	C22H26N2O3
Molecular Weight	366.46 g/mol
Synonyms	17-Methoxycorynan-16-carboxylic acid methyl ester, (16E)-17-Methoxy-16,17-didehydrocorynan-16-carboxylic acid methyl ester; Methyl (3β,16E,20β)-16,17-didehydro-17-methoxycorynan-16-carboxylate; 16,17-Didehydro-17-methoxycorynan-16-carboxylic acid methyl ester; Corynan derivative; Indole alkaloid ester.
EINECS	Contact for details

Quality Control

Our (3β,16E,20β)-16,17-Didehydro-17-Methoxycorynan-16-Carboxylic Acid Methyl Ester is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the stringent requirements for research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting purity, assay, and relevant physical data.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and should be handled under inert atmosphere to minimize risk of degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Assay	≥ 97.0%
Loss on Drying	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.