Description

N5-[[(Aminoiminomethyl)Amino]Carbonyl]-L-Ornithine is a specialized amino acid derivative of significant interest in biochemical and pharmaceutical research. This compound serves as a crucial intermediate and a potent, selective inhibitor of nitric oxide synthase (NOS), making it a valuable tool for studying cellular signaling pathways. It is primarily utilized by research institutions and pharmaceutical developers focused on cardiovascular, neurological, and inflammatory disease mechanisms. Its precise structure allows for targeted investigation into arginine metabolism and nitric oxide biology.

Application

• Biochemical Research: As a key inhibitor (Nω-amino-L-arginine, L-NAA) for studying nitric oxide synthase (NOS) isoforms in enzymatic assays and cell-based studies.
• Pharmaceutical Development: Serves as a critical intermediate or reference standard in the discovery and development of novel therapeutics targeting conditions like sepsis, hypertension, and neurodegeneration.
• Academic Research: Used in university and institutional labs to explore the role of nitric oxide in vasodilation, immune response, and neural communication.
• Diagnostic Reagent Manufacturing: Potential use in the formulation of specialized kits and reagents for clinical research and diagnostic applications related to NO pathways.
• Metabolic Pathway Analysis: A tool compound for investigating the urea cycle and arginine-citrulline-NO metabolic axis in various biological models.

Basic Information

Product Name	N5-[[(Aminoiminomethyl)Amino]Carbonyl]-L-Ornithine
CAS No.	7536-90-5
Molecular Formula	C7H16N6O3
Molecular Weight	232.24 g/mol
Synonyms	Nω-Amino-L-arginine; L-NAA; NG-Amino-L-arginine; (S)-2-Amino-5-[(aminoiminomethyl)amino]pentanoic acid; N5-(Aminoiminomethyl)-L-ornithine; Nitric Oxide Synthase Inhibitor I; L-N5-(1-Iminoethyl)ornithine (common mis-association); N5-Carbamimidamido-L-ornithine
EINECS	Contact for details

Quality Control

Our N5-[[(Aminoiminomethyl)Amino]Carbonyl]-L-Ornithine is produced under strict quality management systems to ensure high purity and batch-to-batch consistency suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant standards for research-grade biochemicals, ensuring reliable performance in your experimental systems.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Optical Rotation	[α]D20: Contact for details
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.