Description

Sodium n-[4-[[(2,4-Diamino-6-Pteridinyl)Methyl]Methylamino]Benzoyl]-L-Glutamate CAS NO 7532-04-9 is the sodium salt of a key folic acid derivative, serving as a critical pharmaceutical intermediate and biochemical reagent. This compound is essential for research and production processes requiring high-purity folate analogs. It is primarily utilized by manufacturers in the pharmaceutical, biotechnology, and advanced life science sectors for the synthesis of active pharmaceutical ingredients (APIs), diagnostic reagents, and specialized cell culture media.

Application

• Pharmaceutical Intermediate: A vital building block in the synthesis of folic acid-based drugs and therapeutic agents.
• Biochemical Research: Used as a precursor or standard in enzymatic studies, metabolic pathway analysis, and folate-related biochemical assays.
• Cell Culture & Media Formulation: Incorporated into specialized cell culture media formulations that require defined folate sources for cell growth studies.
• Diagnostic Reagent Production: Serves as a key component in the manufacture of diagnostic kits and reagents for clinical testing.
• Reference Standard: Employed as a high-purity analytical reference standard for quality control and method validation in laboratories.
• Nutritional Science Research: Used in studies investigating folate metabolism, bioavailability, and fortification.

Basic Information

Product Name	Sodium n-[4-[[(2,4-Diamino-6-Pteridinyl)Methyl]Methylamino]Benzoyl]-L-Glutamate
CAS No.	7532-04-9
Molecular Formula	C20H21N8NaO5
Molecular Weight	476.43 g/mol
Synonyms	Sodium Folate Derivative; Sodium Pteroylglutamate Derivative; N-[4-[[(2,4-Diamino-6-pteridinyl)methyl]methylamino]benzoyl]-L-glutamic acid sodium salt; Folate Sodium Salt Analog; L-Glutamic acid, N-[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-, sodium salt; Prefolic A sodium salt; Aminopterin derivative sodium salt
EINECS	Contact for details

Quality Control

Our Sodium n-[4-[[(2,4-Diamino-6-Pteridinyl)Methyl]Methylamino]Benzoyl]-L-Glutamate is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets exacting standards for pharmaceutical and research use. Certificates of Analysis (COA) detailing purity, impurities, and other critical parameters are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals (as Pb)	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.