Description

Adenylylmethylenediphosphonate Sodium Salt is a high-purity, nucleotide-based bisphosphonate compound of significant interest in biochemical and pharmaceutical research. Its unique structure, which combines an adenosine moiety with a methylenediphosphonate group, makes it a valuable tool for studying enzyme mechanisms and metabolic pathways. This product is essential for researchers and manufacturers in the life sciences sector, particularly those focused on nucleotide metabolism, bone biology, and the development of novel therapeutic agents.

Application

• Enzymology Research: Acts as a potent, non-hydrolyzable ATP analog for studying ATP-dependent enzymes, kinases, and phosphotransferases.
• Metabolic Pathway Studies: Used to investigate and modulate nucleotide metabolism and energy transfer processes in cellular systems.
• Bone Metabolism Research: Serves as a reference compound or precursor in the study of bisphosphonate action on osteoclast activity and bone resorption.
• Pharmaceutical Development: Employed as a key intermediate or reference standard in the R&D of novel nucleotide-based therapeutics.
• Biochemical Assays: Utilized as a substrate or inhibitor in high-throughput screening assays and diagnostic test development.
• Academic & Industrial R&D: A critical reagent for universities, contract research organizations (CROs), and biotech companies exploring nucleotide signaling.

Basic Information

Product Name	Adenylylmethylenediphosphonate Sodium Salt
CAS No.	7414-56-4
Molecular Formula	C11H15N5O12P3Nan (n=3-5)
Molecular Weight	Approx. 605.0 (Free acid). Contact for details on specific salt form.
Synonyms	Adenosine 5'-(α,β-Methylenetriphosphate), Sodium Salt; AMP-PCP, Sodium Salt; Adenylyl Methylenediphosphonate; Adenosine-5'-[α,β-methyleno]triphosphate; ATP-α,β-CH2-ATP; Non-hydrolyzable ATP analog; β,γ-Methylenetriphosphoadenosine; P1,P2-Di(adenosine-5')-P3-methylenetriphosphate (related compound).
EINECS	Contact for details.

Quality Control

Our Adenylylmethylenediphosphonate Sodium Salt is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity for research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation. Certificates of Analysis (COA) detailing all test results are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This material is hygroscopic (moisture-sensitive). For long-term storage, consider desiccation. Allow the sealed container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water, slightly soluble in methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.