Description

Phenylthiohydantoin Glutamic Acid (CAS 7390-22-9) is a specialized derivative of glutamic acid, primarily utilized as a key intermediate in peptide and amino acid research. This compound is critical for analytical and synthetic chemistry workflows, particularly in the sequencing and modification of peptides. It is an essential material for research institutions, pharmaceutical development labs, and fine chemical manufacturers focused on advanced biochemical synthesis.

Application

• Peptide Sequencing: Serves as a critical reagent in the Edman degradation process for determining the amino acid sequence of peptides and proteins.
• Pharmaceutical Intermediate: Used in the research and development of novel therapeutic peptides and peptidomimetics.
• Biochemical Research: Acts as a standard or reference compound in analytical methods such as HPLC and mass spectrometry for amino acid analysis.
• Proteomics Studies: Employed in laboratories studying protein structure, function, and post-translational modifications.
• Fine Chemical Synthesis: A building block for the synthesis of more complex, custom-designed amino acid derivatives and conjugates.

Basic Information

Product Name	Phenylthiohydantoin Glutamic Acid
CAS No.	7390-22-9
Molecular Formula	C₁₄H₁₆N₂O₅S
Molecular Weight	324.35 g/mol
Synonyms	PTH-Glutamic Acid; 2-[(Phenylcarbamothioyl)amino]pentanedioic acid; Glutamic Acid Phenylthiohydantoin; PTH-Glu; Edman Degradation Reagent for Glutamic Acid; N-Phenylthiocarbamoylglutamic Acid; (2S)-2-[[(Phenylamino)carbothioyl]amino]pentanedioic acid
EINECS	Contact for details

Quality Control

Our Phenylthiohydantoin Glutamic Acid is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency suitable for sensitive research applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing key parameters such as purity, identity, and impurity profiles. Our quality system is designed to meet the rigorous standards expected in pharmaceutical and analytical research environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.