Description

Adenosine 5'-[Hydrogen [[Hydroxy(Phosphonooxy)Phosphinyl]Methyl]Phosphonate] is a high-purity, modified nucleotide analog of significant interest in biochemical and pharmaceutical research. This compound serves as a critical tool molecule for studying nucleotide metabolism, enzyme kinetics, and signal transduction pathways. It is primarily utilized by researchers and manufacturers in the life sciences sector, particularly in enzymology, molecular biology, and the development of novel therapeutic agents.

Application

• Enzyme Substrate & Inhibitor Studies: Acts as a substrate or competitive inhibitor for kinases, phosphatases, and other ATP-dependent enzymes to elucidate reaction mechanisms.
• Biochemical Research Reagent: Used in the study of purinergic signaling pathways and nucleotide-mediated cellular processes.
• Pharmaceutical Intermediate: Serves as a key synthetic building block for the development of nucleotide-based prodrugs and antiviral compounds.
• Diagnostic Kit Development: Employed in the formulation of assay kits for monitoring enzymatic activity and high-throughput screening (HTS) platforms.
• Metabolic Pathway Analysis: Utilized as a tracer or analog in metabolic flux studies to investigate energy metabolism in cells.

Basic Information

Product Name	Adenosine 5'-[Hydrogen [[Hydroxy(Phosphonooxy)Phosphinyl]Methyl]Phosphonate]
CAS No.	7292-42-4
Molecular Formula	C11H18N5O12P3
Molecular Weight	529.20 g/mol
Synonyms	Adenosine 5'-(α,β-Methylenetriphosphate); Adenosine 5'-[α,β-Methylene]triphosphate; AMPPCP; Ado-5'-PP[CH2]P; α,β-Methylene-ATP; Adenosine 5'-(α,β-Methylenetriphosphoric Acid); ATP-α,β-CH2; CAS 7292-42-4
EINECS	Contact for details

Quality Control

Our Adenosine 5'-[Hydrogen [[Hydroxy(Phosphonooxy)Phosphinyl]Methyl]Phosphonate] is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry, cool place. This material is hygroscopic (moisture-sensitive). Allow the sealed container to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Assay	≥ 90% (by weight)
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.