Description

1-Stearoyl-2-Linoleoyl-Sn-Glycero-3-Phosphoethanolamine is a high-purity, semi-synthetic phospholipid with a defined fatty acid composition, serving as a critical building block for advanced lipid-based formulations. Its value lies in providing a consistent and well-characterized molecular structure, which is essential for achieving reproducible performance in sensitive applications. This compound is primarily needed by researchers and manufacturers in the pharmaceutical, biotechnology, and advanced cosmetics industries for developing liposomes, lipid nanoparticles, and other sophisticated delivery systems.

Application

• Liposome and Lipid Nanoparticle (LNP) Formulation: A key structural phospholipid for constructing stable, uniform vesicles for drug and gene delivery.
• Biomembrane Research: Used as a model membrane component to study lipid bilayer properties, protein-lipid interactions, and membrane fluidity.
• Cosmetic Actives Delivery: Incorporated into nanocarriers to enhance the skin penetration and stability of active ingredients in high-end skincare products.
• Diagnostic Reagent Development: Serves as a functional lipid in the preparation of diagnostic kits and assays requiring specific membrane environments.
• Cell Culture Media Supplement: Used in specialized cell culture applications to provide essential lipid components for cell growth and membrane integrity.
• Biophysical Studies: Employed in research involving fluorescence anisotropy, calorimetry, and other techniques to understand membrane dynamics.

Basic Information

Product Name	1-Stearoyl-2-Linoleoyl-Sn-Glycero-3-Phosphoethanolamine
CAS No.	7266-53-7
Molecular Formula	C43H80NO8P
Molecular Weight	770.07 g/mol
Synonyms	SLPE; 1-Stearoyl-2-linoleoyl-sn-glycero-3-phosphoethanolamine; PE(18:0/18:2); Phosphatidylethanolamine (18:0/18:2); (2R)-2,3-Bis[[(Z)-octadec-9-enoyl]oxy]propyl 2-(trimethylazaniumyl)ethyl phosphate; 1-Octadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphoethanolamine; L-α-Phosphatidylethanolamine, β′-stearoyl-γ′-linoleoyl-
EINECS	Contact for details

Quality Control

Our 1-Stearoyl-2-Linoleoyl-Sn-Glycero-3-Phosphoethanolamine is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity suitable for research and formulation. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing key parameters such as identity, purity, and fatty acid composition. We adhere to relevant GMP and ISO 9001 standards in our manufacturing processes to guarantee product integrity and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to minimize oxidation and hydrolysis. For long-term storage, desiccate at -20°C. Allow the sealed container to reach room temperature before opening to prevent condensation and moisture ingress.

Specification

Item	Specification
Appearance	White to off-white powder or waxy solid
Identification (HPLC/MS)	Complies
Assay (HPLC)	≥ 95.0%
Fatty Acid Composition (GC)	Stearic Acid (C18:0): 45-55% Linoleic Acid (C18:2): 45-55%
Water Content (KF)	≤ 2.0%
Peroxide Value	≤ 5.0 meq/kg
Solubility	Soluble in chloroform, ethanol; insoluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.