Description

N,N'-Ethylenebis(Iodoacetamide) is a specialized bifunctional alkylating agent and cross-linking reagent of significant interest in advanced chemical synthesis and life science research. Its core value lies in its ability to introduce iodoacetamide moieties, making it a powerful tool for modifying proteins, peptides, and other biomolecules by targeting thiol groups. This compound is essential for researchers and manufacturers in the fields of bioconjugation, proteomics, and pharmaceutical intermediate synthesis, where precise molecular modification is required.

Application

• Bioconjugation Reagent: Used for site-specific modification of cysteine residues in proteins and antibodies for drug conjugation (ADC development) and diagnostic assays.
• Proteomics Research: Acts as a cross-linker or affinity label to study protein structure, function, and protein-protein interactions.
• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of more complex therapeutic agents and bioactive molecules.
• Polymer Chemistry: Employed in the synthesis and modification of functional polymers and hydrogels with tailored properties.
• Chemical Biology Tool: Utilized for labeling and immobilizing biomolecules on surfaces for biosensor and microarray applications.
• Enzyme Inhibitor Studies: Used to create irreversible inhibitors by covalently binding to active-site thiols of enzymes.

Basic Information

Product Name	N,N'-Ethylenebis(Iodoacetamide)
CAS No.	7250-43-3
Molecular Formula	C6H8I2N2O2
Molecular Weight	409.95 g/mol
Synonyms	1,1'-(Ethane-1,2-diyl)bis(2-iodoacetamide); Ethylenebis(iodoacetamide); N,N'-Ethylene-bis(iodoacetamide); 1,2-Bis(iodoacetamido)ethane; Iodoacetamide ethylene dimer; Bis(iodoacetamido)ethane; EBI; Contact for EINECS details.

Quality Control

Our N,N'-Ethylenebis(Iodoacetamide) is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and synthesis applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its light-sensitive nature, prolonged exposure to light should be avoided to maintain product stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Loss on Drying	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.