Description

2'-Deoxy-5-Fluorouridine 3',5'-Dipentanoate is a chemically modified nucleoside derivative, specifically a protected prodrug form of the active metabolite 5-fluorouracil. This compound is of significant value in pharmaceutical research and development as a key synthetic intermediate for creating novel chemotherapeutic agents and antiviral drugs. It is primarily needed by research institutions, pharmaceutical manufacturers, and fine chemical suppliers engaged in the development of nucleoside-based therapeutics, particularly for oncology and virology applications.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of advanced nucleoside analog prodrugs for cancer therapy.
• Anticancer Agent Research: Used in preclinical and clinical research to develop novel fluoropyrimidine-based chemotherapeutics targeting DNA synthesis.
• Antiviral Drug Development: Serves as a precursor in the synthesis of potential antiviral compounds that inhibit viral polymerase enzymes.
• Biochemical Research: Employed in studies investigating cell proliferation, nucleotide metabolism, and the mechanism of action of fluorouracil derivatives.
• Process Chemistry & Scale-Up: Utilized by fine chemical manufacturers for the kilogram-scale production of active pharmaceutical ingredients (APIs).
• Reference Standard: Acts as a high-purity analytical standard for quality control and method development in pharmaceutical laboratories.

Basic Information

Product Name	2'-Deoxy-5-Fluorouridine 3',5'-Dipentanoate
CAS No.	7207-62-7
Molecular Formula	C20H27FN2O8
Molecular Weight	442.44 g/mol
Synonyms	5-Fluoro-2'-deoxyuridine 3',5'-dipentanoate; 5-Fluoro-2'-deoxyuridine 3',5'-divalerate; 5-FdUrd 3',5'-dipentanoate; 2'-Deoxy-5-fluorouridine divalerate; 5-Fluorodeoxyuridine dipentanoate; FdUDP; 1-[(2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-fluoro-1,2,3,4-tetrahydropyrimidine-2,4-dione 3',5'-dipentanoate
EINECS	Contact for details

Quality Control

Our 2'-Deoxy-5-Fluorouridine 3',5'-Dipentanoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.