Description

Doxycycline CAS NO 7164-70-7 is a broad-spectrum, semi-synthetic tetracycline-class antibiotic. It is valued for its high potency, excellent bioavailability, and effectiveness against a wide range of gram-positive and gram-negative bacteria, as well as atypical pathogens. This makes it a critical active pharmaceutical ingredient (API) for manufacturers in the pharmaceutical, veterinary medicine, and aquaculture industries.

Application

• Human Pharmaceutical Formulations: Primary API for oral capsules, tablets, and injectables to treat respiratory infections, Lyme disease, acne, and malaria prophylaxis.
• Veterinary Medicine: Used in medicated feeds, powders, and injectables for treating bacterial infections in livestock, poultry, and companion animals.
• Aquaculture: Incorporated into fish feed to control and prevent bacterial diseases in farmed fish and shrimp.
• Research & Development: Serves as a key biochemical tool in microbiological research and antibiotic resistance studies.
• Industrial Biocontrol: Potential use in specialized fermentation processes and as a selective agent in cell culture media.

Basic Information

Product Name	Doxycycline
CAS No.	7164-70-7
Molecular Formula	C₂₂H₂₄N₂O₈
Molecular Weight	444.43 g/mol
Synonyms	Doxycycline Hydate; Doxycycline Monohydrate; 6-Deoxy-5-oxytetracycline; Vibramycin; Doxylin; GS-3065; (4S,4aR,5S,5aR,6R,12aS)-4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxonaphthacene-2-carboxamide Monohydrate
EINECS	230-524-9

Quality Control

Our Doxycycline is manufactured under strict quality management systems. It can be supplied to meet various pharmacopoeial standards, including USP, EP, and BP, ensuring compliance for global pharmaceutical applications. Every batch is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We are committed to providing materials that meet the stringent requirements of cGMP and regulatory submissions.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to protect from moisture. Keep away from incompatible substances.

Specification

Item	Specification
Appearance	Yellow to light yellow crystalline powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms to reference standard
Assay (HPLC, anhydrous basis)	98.0% - 102.0%
Water Content (KF)	1.5% - 3.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 2.0%
Specific Optical Rotation	-105° to -120°

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.