Description

Thiocholine Iodide is a high-purity biochemical reagent essential for enzymatic research and diagnostic applications. Its primary value lies in its role as a specific substrate for cholinesterase enzymes, enabling precise measurement of enzyme activity. This compound is critically needed by researchers and manufacturers in the pharmaceutical, clinical diagnostics, and agrochemical industries for developing assays and quality control protocols.

Application

• Enzymatic Assay Substrate: Primary substrate for the colorimetric and electrochemical determination of acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE) activity.
• Clinical Diagnostics: Used in diagnostic kits for detecting organophosphate and carbamate pesticide exposure, as well as for monitoring liver function.
• Neuropharmacology Research: Essential tool for studying cholinesterase inhibitors, which are relevant to Alzheimer's disease, myasthenia gravis, and nerve agent research.
• Biosensor Development: Key component in the fabrication of amperometric biosensors for environmental monitoring of neurotoxic agents.
• Agrochemical Screening: Employed in high-throughput screening assays to evaluate the efficacy and toxicity of new insecticide formulations.
• Forensic Toxicology: Utilized in laboratory methods to confirm and quantify anticholinesterase poisoning.

Basic Information

Product Name	Thiocholine Iodide
CAS No.	7161-73-1
Molecular Formula	C5H14INS
Molecular Weight	231.14 g/mol
Synonyms	(2-Mercaptoethyl)trimethylammonium Iodide; 2-Mercapto-N,N,N-trimethylethanaminium Iodide; S-(2-Trimethylammonioethyl) Thioiodide; Ethanaminium, 2-mercapto-N,N,N-trimethyl-, iodide; Acetylthiocholine Iodide precursor; Cholinesterase Substrate; TChI
EINECS	230-525-2

Quality Control

Our Thiocholine Iodide is manufactured under strict quality management systems to ensure batch-to-batch consistency and reliability for sensitive research applications. Each lot undergoes comprehensive analytical testing including HPLC for purity, identity confirmation by IR and NMR, and stringent limits for residual solvents and heavy metals. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with our rigorous in-house specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to prevent decomposition. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Heavy Metals (as Pb)	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines
Use Test (Enzymatic Activity)	Pass

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.