Description

1,3,4,6-Tetra-o-Acetyl-2-Deoxy-2-Trifluoracetamido-D-Glucose is a key fluorinated carbohydrate derivative, serving as a critical advanced intermediate in the synthesis of complex bioactive molecules. Its value lies in providing a protected, reactive scaffold for introducing the 2-amino-2-deoxy sugar moiety with a stable trifluoroacetamide protecting group. This compound is essential for researchers and manufacturers in pharmaceutical development, particularly for producing novel antibiotics, antiviral agents, and glycoconjugate vaccines.

Application

• Pharmaceutical Intermediate: A vital building block for the synthesis of glycosidase inhibitors and nucleoside analogs with potential therapeutic activity.
• Glycobiology Research: Used in the chemical and enzymatic synthesis of complex oligosaccharides and glycopeptides for structure-activity relationship studies.
• Antiviral Drug Development: Serves as a precursor in the creation of neuraminidase inhibitors and other antiviral compounds targeting viral glycoproteins.
• Antibiotic Synthesis: Employed in the production of novel aminoglycoside and macrolide antibiotics where the sugar moiety is crucial for bioactivity.
• Probe and Diagnostic Agent Development: Useful for creating fluorinated carbohydrate probes for imaging and diagnostic applications, leveraging the properties of the fluorine atom.
• Conjugate Vaccine Preparation: Acts as an activated sugar donor for coupling to carrier proteins in the development of synthetic conjugate vaccines.

Basic Information

Product Name	1,3,4,6-Tetra-o-Acetyl-2-Deoxy-2-Trifluoracetamido-D-Glucose
CAS No.	7139-63-1
Molecular Formula	C₁₆H₂₀F₃NO₁₀
Molecular Weight	443.33 g/mol
Synonyms	2-Deoxy-2-trifluoroacetamido-D-glucose tetraacetate; 2-Trifluoroacetamido-2-deoxy-D-glucose tetraacetate; N-Trifluoroacetyl-D-glucosamine tetraacetate; 1,3,4,6-Tetra-O-acetyl-2-deoxy-2-(trifluoroacetamido)-β-D-glucopyranose; Peracetylated N-trifluoroacetylglucosamine; GlcNTFA tetraacetate; 2-Acetamido-1,3,4,6-tetra-O-acetyl-2-deoxy-β-D-glucopyranose (related analog); TFA-GlcNAc tetraacetate
EINECS	Contact for details

Quality Control

Our 1,3,4,6-Tetra-o-Acetyl-2-Deoxy-2-Trifluoracetamido-D-Glucose is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical R&D and production. Certificates of Analysis (COA) with detailed chromatographic data (HPLC, GC) are provided and available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent decomposition. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.