Description

D-Erythro-C18-Dihydro-D-Sphingosine is a high-purity, synthetic sphingoid base, a fundamental building block in lipid biochemistry and pharmaceutical research. This compound is critical for studying and modulating sphingolipid metabolism, which governs key cellular processes like apoptosis, proliferation, and signaling. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and advanced life science sectors developing novel therapeutics and diagnostic tools.

Application

• Biochemical Research: A key intermediate and standard for investigating sphingolipid pathways, enzyme kinetics (e.g., ceramide synthases), and metabolic disorders.
• Pharmaceutical Synthesis: Serves as a crucial chiral precursor for the synthesis of complex sphingolipids, ceramides, and novel drug candidates targeting cancer, inflammation, and neurological diseases.
• Cell Biology & Signaling Studies: Used to explore the role of dihydrosphingosine in cell membrane structure, stress responses, and intracellular signal transduction mechanisms.
• Reference Standard: Employed as a high-purity analytical standard in HPLC, LC-MS, and other chromatographic methods for quality control and metabolic profiling.
• Lipidomics: An essential component in lipid libraries for mass spectrometry-based identification and quantification of sphingolipid species in biological samples.
• Cosmeceutical R&D: Investigated for its potential role in skin barrier function and as a precursor for bioactive lipids in advanced skincare formulations.

Basic Information

Product Name	D-Erythro-C18-Dihydro-D-Sphingosine
CAS No.	764-22-7
Molecular Formula	C18H39NO2
Molecular Weight	301.51 g/mol
Synonyms	(2S,3R)-2-Amino-1,3-octadecanediol; D-erythro-Dihydrosphingosine; D-erythro-Sphinganine; (2S,3R)-2-Aminooctadecane-1,3-diol; C18-Dihydro-D-sphingosine; D-erythro-1,3-Dihydroxy-2-aminooctadecane; D-erythro-C18-Sphinganine; 764-22-7
EINECS	Contact for details

Quality Control

Our D-Erythro-C18-Dihydro-D-Sphingosine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (NMR, MS), to ensure it meets the high standards required for research and pharmaceutical applications. A Certificate of Analysis (COA) detailing purity, specific rotation, and chromatographic data is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to warm to room temperature before opening to prevent condensation and moisture ingress.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.