Description

Rolitetracycline CAS NO 751-97-3 is a semi-synthetic, broad-spectrum antibiotic belonging to the tetracycline class. It is valued for its efficacy against a wide range of Gram-positive and Gram-negative bacteria, as well as certain atypical pathogens. This compound is primarily utilized in the pharmaceutical industry for research and development, serving as a key intermediate or active pharmaceutical ingredient (API) in the formulation of veterinary and human medicinal products.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of advanced tetracycline-based antibiotic formulations.
• Veterinary Medicine: Used in the development of treatments for bacterial infections in livestock and companion animals.
• Microbiological Research: Employed as a standard or tool compound in studies investigating bacterial resistance mechanisms and antibiotic efficacy.
• API Manufacturing: Acts as the active pharmaceutical ingredient in the production of specific antibiotic preparations under controlled GMP environments.
• Reference Standard: Utilized in quality control laboratories as a high-purity reference material for analytical method development and validation.

Basic Information

Product Name	Rolitetracycline
CAS No.	751-97-3
Molecular Formula	C₂₇H₃₃N₃O₈
Molecular Weight	527.57 g/mol
Synonyms	Rolitetracycline; BRN 0091132; Pyrrolidinomethyltetracycline; Reverin; Syntetrin; Syntodecin; Tetracycline, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, (4S,4aS,5aS,6S,12aS)-, compd. with pyrrolidine (1:1); (4S,4aS,5aS,6S,12aS)-4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide compound with pyrrolidine (1:1)
EINECS	Contact for details

Quality Control

Our Rolitetracycline is produced and tested to meet high-purity standards suitable for pharmaceutical research and development. Each batch undergoes rigorous analytical testing, including HPLC for assay and related substances, to ensure identity, purity, and strength. A comprehensive Certificate of Analysis (COA) documenting all test results is provided with every shipment to guarantee traceability and compliance with your quality requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	Yellow to yellowish-brown powder
Identification (IR)	Conforms to standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.