Description

(2Z,4R,4As,5As,6S,12As)-2-(Amino-Hydroxy-Methylidene)-4-Dimethylamino- 6,10,11,12A-Tetrahydroxy-6-Methyl-4,4A,5,5A-Tetrahydrotetracene-1,3,12 -Trione is a complex tetracyclic compound of significant interest in advanced chemical synthesis and research. This molecule matters for its intricate stereochemistry and functional group array, which serve as a valuable scaffold for developing novel bioactive compounds. It is primarily needed by research institutions and pharmaceutical development laboratories engaged in the synthesis of new chemical entities, particularly in antibiotic and anticancer research.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block in the research and development of novel tetracycline-class antibiotics and other therapeutic agents.
• Chemical Synthesis Research: Used as a sophisticated starting material or intermediate in complex organic synthesis, especially for constructing polycyclic systems.
• Biochemical Research: Investigated for its potential biological activity and interactions with enzymes or receptors due to its structural similarity to bioactive natural products.
• Reference Standard: Employed as a high-purity analytical standard in quality control laboratories for method development and compound identification.
• Academic Research: Utilized in university and institutional labs for studies in stereochemistry, total synthesis, and medicinal chemistry.

Basic Information

Product Name	(2Z,4R,4As,5As,6S,12As)-2-(Amino-Hydroxy-Methylidene)-4-Dimethylamino- 6,10,11,12A-Tetrahydroxy-6-Methyl-4,4A,5,5A-Tetrahydrotetracene-1,3,12 -Trione
CAS No.	79-85-6
Molecular Formula	C₂₂H₂₄N₂O₈
Molecular Weight	444.44 g/mol
Synonyms	2-(Amino-hydroxy-methylidene)-4-dimethylamino-6,10,11,12a-tetrahydroxy-6-methyl-4,4a,5,5a-tetrahydrotetracene-1,3,12-trione; Anhydrotetracycline; ATC; 4-Dimethylamino-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide; 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-; NSC 643131; Tetracycline, 5a(11a)-dehydro-; 5a,6-Anhydrotetracycline
EINECS	201-231-7

Quality Control

Our (2Z,4R,4As,5As,6S,12As)-2-(Amino-Hydroxy-Methylidene)-4-Dimethylamino- 6,10,11,12A-Tetrahydroxy-6-Methyl-4,4A,5,5A-Tetrahydrotetracene-1,3,12 -Trione is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. Due to its hygroscopic (moisture-sensitive) nature, it is recommended to store the product under an inert atmosphere or in a desiccator to maintain stability and prevent degradation. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	Yellow to orange-yellow powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.