Description

5-Fluoro-1-(2'-Fluoro-2'-Deoxyribofuranosyl)Uracil is a fluorinated nucleoside analog of significant interest in pharmaceutical research and development. This compound serves as a critical intermediate in the synthesis of antiviral and anticancer agents, particularly those targeting viral replication and cellular proliferation. It is primarily utilized by research institutions, pharmaceutical manufacturers, and fine chemical suppliers engaged in the development of novel therapeutics.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of antiviral drugs, including nucleoside reverse transcriptase inhibitors.
• Anticancer Research: Used in the development and study of chemotherapeutic agents that interfere with DNA synthesis in cancer cells.
• Biochemical Research: Employed as a substrate or inhibitor in enzymatic studies related to thymidylate synthase and other nucleotide-metabolizing enzymes.
• Prodrug Synthesis: Serves as a precursor for the creation of prodrugs designed to improve bioavailability and targeting.
• Reference Standard: Used as a high-purity analytical standard in quality control laboratories for method development and validation.
• Life Science Reagents: Incorporated into specialized kits and reagents for molecular biology and diagnostic applications.

Basic Information

Product Name	5-Fluoro-1-(2'-Fluoro-2'-Deoxyribofuranosyl)Uracil
CAS No.	72-84-4
Molecular Formula	C9H10F2N2O5
Molecular Weight	264.18 g/mol
Synonyms	5-Fluoro-2'-deoxyuridine; 5-Fluoro-2'-deoxyuridine, 2'-Fluoro-; 2'-Fluoro-5-fluoro-2'-deoxyuridine; 5-Fluoro-1-(2-deoxy-2-fluoro-β-D-ribofuranosyl)uracil; FdUrd; 5-Fluoro-2'-fluoro-2'-deoxyuridine; NSC 27640; 2'-F-5-FdUrd
EINECS	Contact for details

Quality Control

Our 5-Fluoro-1-(2'-Fluoro-2'-Deoxyribofuranosyl)Uracil is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the stringent requirements for pharmaceutical research. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm
Related Substances (HPLC)	Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.