Description

β-Nicotinamide Adenine Dinucleotide Phosphate Sodium Salt is the sodium salt of the reduced form of nicotinamide adenine dinucleotide phosphate (NADPH), a critical coenzyme in numerous biological redox reactions. This high-purity biochemical is essential for research and industrial processes requiring a reliable source of reducing equivalents. It is primarily utilized by the pharmaceutical, biotechnology, and diagnostic industries for enzymatic assays, metabolic studies, and as a key reagent in biosynthetic pathways.

Application

• Enzymatic Assays & Diagnostic Kits: Serves as an essential cofactor in spectrophotometric and fluorometric assays for enzymes like dehydrogenases, reductases, and cytochrome P450 isoforms.
• Pharmaceutical Research & Development: Used in drug discovery and metabolic pathway studies to investigate redox mechanisms and cellular energy metabolism.
• Biocatalysis & Industrial Enzymology: Acts as a co-substrate in enzymatic synthesis for the production of chiral intermediates, fine chemicals, and active pharmaceutical ingredients (APIs).
• Cell Culture & Fermentation: Employed in specialized media formulations to support cellular metabolism and redox balance in research-scale bioprocesses.
• Antioxidant Research: Utilized in studies of oxidative stress, where NADPH is required for the regeneration of glutathione and other antioxidant systems.
• Food & Cosmetic Ingredient Analysis: Applied in analytical methods for determining specific enzyme activities relevant to quality control and safety testing.

Basic Information

Product Name	β-Nicotinamide Adenine Dinucleotide Phosphate Sodium Salt
CAS No.	698999-85-8
Molecular Formula	C21H26N7Na4O17P3 (for tetrasodium salt)
Molecular Weight	833.36 g/mol (for tetrasodium salt)
Synonyms	NADPH Tetrasodium Salt; Reduced Nicotinamide Adenine Dinucleotide Phosphate Sodium Salt; TPNH Sodium Salt; β-NADPH-Na4; Coenzyme II Reduced Form Sodium Salt; Dihydronicotinamide adenine dinucleotide phosphate sodium salt; 2'-(Dihydrogen phosphate) 5'-(trihydrogen pyrophosphate) P'→5'-ester with 1,4-dihydro-1-β-D-ribofuranosyl-3-pyridinecarboxamide sodium salt
EINECS	Contact for details

Quality Control

Our β-Nicotinamide Adenine Dinucleotide Phosphate Sodium Salt is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and industrial applications. Certificates of Analysis (COA) detailing purity, assay, and related substance profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. The product is hygroscopic (moisture-sensitive) and light-sensitive. For long-term stability, store desiccated under inert atmosphere. Allow the sealed container to reach room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/UV)	Conforms
Purity (HPLC)	≥ 95%
Assay (Enzymatic)	≥ 90%
Water Content (KF)	≤ 5.0%
pH (1% Solution)	7.0 - 9.0
Solubility (in Water)	Clear, colorless solution

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.