Description

(1R)-1-(3-Methoxyphenyl)Butylamine is a chiral amine building block of significant importance in modern synthetic chemistry. Its value lies in its role as a key intermediate for constructing complex molecules with specific stereochemistry, which is critical for achieving desired biological activity. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials. The product is supplied with a high level of purity and batch-to-batch consistency to meet the stringent demands of process development and scale-up.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and cardiovascular therapeutic areas.
• Agrochemical Research: Used in the development of enantiomerically pure pesticides and herbicides, where the specific stereoisomer can dictate efficacy and environmental safety.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for synthesizing chiral ligands used in asymmetric hydrogenation and other catalytic transformations.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex natural products, flavors, and fragrances requiring precise stereocontrol.
• Material Science: Potential building block for chiral polymers or liquid crystals with specialized optical properties.

Basic Information

Product Name	(1R)-1-(3-Methoxyphenyl)Butylamine
CAS No.	698378-52-8
Molecular Formula	C11H17NO
Molecular Weight	179.26 g/mol
Synonyms	(R)-1-(3-Methoxyphenyl)butan-1-amine; (1R)-1-(3-Methoxyphenyl)-1-butanamine; (R)-3'-Methoxy-α-ethylbenzylamine; (R)-1-(m-Methoxyphenyl)butylamine; (R)-(-)-1-(3-Methoxyphenyl)butylamine; (R)-m-Methoxy-α-ethylbenzylamine; (1R)-1-(3-Methoxyphenyl)butylamine
EINECS	Contact for details

Quality Control

Every batch of (1R)-1-(3-Methoxyphenyl)Butylamine is produced and tested under a strict quality management system. Our products undergo rigorous quality testing, including chiral purity analysis, to ensure compliance with customer specifications and industry standards for advanced intermediates. A comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profile is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.