Description

7-Acetylintermedine n-Oxide is a pyrrolizidine alkaloid derivative, a class of compounds of significant interest in biochemical and pharmacological research. This high-purity reference standard is critical for analytical method development, toxicology studies, and quality control in the pharmaceutical and natural product industries. It is primarily utilized by research institutions, contract research organizations (CROs), and manufacturers requiring precise analytical standards for the identification and quantification of pyrrolizidine alkaloids in complex matrices.

Application

• Pharmaceutical Reference Standard: Serves as a certified reference material (CRM) for the calibration of analytical instruments and validation of testing methods in drug development and quality control laboratories.
• Toxicological Research: Used as a key analyte in studies investigating the metabolism, hepatotoxicity, and carcinogenicity of pyrrolizidine alkaloids, which are important natural toxins.
• Natural Product Analysis: Essential for the accurate identification and quantification of 7-Acetylintermedine n-Oxide and related alkaloids in botanical extracts, herbal medicines, and food supplements to ensure consumer safety.
• Method Development & Validation: Employed by analytical chemists to develop and validate precise HPLC, LC-MS, or GC-MS methods for the separation and detection of complex alkaloid mixtures.
• Regulatory Compliance Testing: Supports compliance testing for regulatory bodies (e.g., FDA, EMA) by providing a traceable standard for assessing contamination levels in raw materials and finished products.
• Academic & Institutional Research: A vital tool for universities and research institutes conducting fundamental studies on plant biochemistry, natural product chemistry, and phytotoxin pathways.

Basic Information

Item	Details
Product Name	7-Acetylintermedine n-Oxide
CAS No.	685132-59-6
Molecular Formula	C17H25NO7
Molecular Weight	355.38 g/mol
Synonyms	7-Acetylintermedine N-Oxide; Intermedine 7-acetate N-oxide; 7-Acetylintermedine Oxide; (1R,7R)-7-[(2S)-2,3-Dihydroxy-2-(1-hydroxyethyl)-3-methylbutanoyl]oxy-1-[(2S)-2-hydroxy-2-(1-methoxyethyl)-3-methylbutyl]-2,3,5,7-tetrahydro-1H-pyrrolizine 1-oxide; 1H-Pyrrolizine-7-acetic acid, 2,3,5,7-tetrahydro-1-hydroxy-1-[(2S)-2-hydroxy-2-(1-methoxyethyl)-3-methylbutyl]-8-methyl-, 7-acetate, 1-oxide, (1R,7R)-
EINECS	Contact for details

Quality Control

Every batch of 7-Acetylintermedine n-Oxide is manufactured under strict quality management systems and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Our quality assurance protocols are designed to meet the rigorous demands of research and regulatory applications. A detailed Certificate of Analysis (COA) providing batch-specific results for identity, assay, purity, and related substances is supplied with each product and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. This product is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.