Description

7-Acetyllycopsamine n-Oxide is a pyrrolizidine alkaloid derivative, a class of compounds of significant interest in pharmacological and biochemical research. This specific acetylated N-oxide serves as a crucial high-purity reference standard and advanced synthetic intermediate. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and specialty chemical manufacturers engaged in the study of natural product chemistry, toxicology, and drug discovery.

Application

• Pharmaceutical Reference Standard: Used for the qualitative and quantitative analysis (HPLC, LC-MS) of pyrrolizidine alkaloids in drug substances, herbal products, and toxicological samples.
• Biochemical Research: Serves as a key intermediate or probe in studying the metabolism, bioactivation, and hepatotoxic mechanisms of pyrrolizidine alkaloids.
• Natural Product Synthesis: Acts as a building block or precursor in the semi-synthesis or total synthesis of complex alkaloids and their analogs for structure-activity relationship (SAR) studies.
• Analytical Method Development: Essential for developing and validating sensitive analytical methods to detect and quantify trace levels of related alkaloid contaminants in food, feed, and botanical extracts.
• Toxicology & Safety Assessment: Employed as a certified material in studies assessing the safety profile and potential genotoxicity of plant-derived ingredients.

Basic Information

Product Name	7-Acetyllycopsamine n-Oxide
CAS No.	685132-58-5
Molecular Formula	C17H27NO7
Molecular Weight	357.40 g/mol
Synonyms	7-Acetyllycopsamine N-oxide; Lycopsamine 7-acetate N-oxide; 7-Acetyllycopsamine N-Oxide; (1R,7aR)-1-[(2S)-3-Acetoxy-2-hydroxy-2-methylbutyl]-2,3,5,7a-tetrahydro-1H-pyrrolizin-7-yl 2-methylbut-2-enoate 1-oxide; 7-Acetyllycopsamine-1-oxide
EINECS	Contact for details

Quality Control

Our 7-Acetyllycopsamine n-Oxide is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC purity analysis, NMR and MS confirmation, to ensure identity, strength, and composition. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, detailing all critical quality attributes to support your research and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, cool, and well-ventilated area. This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere when appropriate to ensure long-term stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.