Description

Z-Val-Arg-4Mβna · Hcl is a specialized peptide derivative, specifically a fluorogenic substrate for proteolytic enzymes. This compound is critical for biochemical research and diagnostic assay development, enabling precise measurement of enzyme activity. It is primarily utilized by pharmaceutical R&D teams, diagnostic manufacturers, and academic researchers focused on protease characterization and inhibitor screening.

Application

• Protease Activity Assays: As a fluorogenic substrate for measuring the kinetic activity of specific proteases like thrombin, trypsin, and related serine proteases.
• Drug Discovery Screening: Used in high-throughput screening (HTS) platforms to identify and characterize novel protease inhibitors for therapeutic development.
• Diagnostic Kit Development: A key component in the formulation of clinical diagnostic tests for coagulation disorders and other protease-related pathologies.
• Biochemical Research: Employed in fundamental enzymology studies to investigate substrate specificity, catalytic mechanisms, and enzyme kinetics.
• Quality Control in Biologics: Monitoring protease activity during the production and purification of biopharmaceuticals to ensure product consistency and safety.

Basic Information

Product Name	Z-Val-Arg-4Mβna · Hcl
CAS No.	679437-50-4
Molecular Formula	C27H43N7O6 · HCl
Molecular Weight	~622.1 g/mol (free base)
Synonyms	Benzyloxycarbonyl-Val-Arg-4-Methoxy-β-naphthylamide Hydrochloride; Z-Val-Arg-4-Methoxy-2-Naphthylamide HCl; Z-Val-Arg-4MNA · HCl; Boc-Val-Arg-4MβNA (common error); Thrombin Substrate; Fluorogenic Peptide Substrate; Protease Substrate 4MβNA; N-Benzyloxycarbonyl-L-valyl-L-arginine 4-methoxy-β-naphthylamide hydrochloride
EINECS	Contact for details

Quality Control

Our Z-Val-Arg-4Mβna · Hcl is manufactured under strict quality systems to ensure batch-to-batch consistency for critical research and diagnostic applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and performance in standard assay conditions. We adhere to relevant guidelines for research-grade biochemicals to guarantee reliable and reproducible results.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and hydrolysis.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in DMSO, DMF; slightly soluble in water
Functional Activity	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.