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Monoethyl Phthalate o-β-D-Glucuronide CAS NO 671215-25-1


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CAS No.:671215-25-1

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Monoethyl Phthalate o-β-D-Glucuronide is a specific glucuronide conjugate of a phthalate derivative, serving as a crucial reference standard and metabolite in advanced biochemical research. This compound is essential for analytical method development, calibration, and quality control in studies concerning phthalate exposure, metabolism, and toxicology. It is primarily utilized by research institutions, pharmaceutical development labs, and contract research organizations (CROs) focused on environmental monitoring, pharmacokinetics, and biomarker discovery.

Application

  • Analytical Reference Standard: Primary use as a high-purity calibrant for the accurate quantification of phthalate metabolites in complex biological matrices via LC-MS/MS or HPLC.
  • Biomarker Research: Critical for developing and validating assays to detect and measure specific phthalate exposure biomarkers in human urine or serum for epidemiological studies.
  • Metabolite Identification: Used as an authentic standard to confirm the identity of monoethyl phthalate glucuronide in metabolism and pharmacokinetic studies of related plasticizers.
  • Toxicology Studies: Employed in research investigating the biotransformation, distribution, and elimination pathways of phthalate esters.
  • Method Development & Validation: Serves as a key component in establishing regulatory-compliant analytical methods for environmental and clinical testing laboratories.
  • Quality Control (QC) Material: Used as an internal standard or system suitability check to ensure the precision and accuracy of analytical instrumentation and procedures.

Basic Information

Product Name Monoethyl Phthalate o-β-D-Glucuronide
CAS No. 671215-25-1
Molecular Formula C17H20O10
Molecular Weight 384.34 g/mol
Synonyms Monoethyl Phthalate Glucuronide; Monoethyl Phthalate β-D-Glucuronide; MEP-Glucuronide; Phthalic Acid Monoethyl Ester Glucuronide; 2-(Carboxymethoxy)benzoic Acid Ethyl Ester Glucuronide; 1-O-[(Ethoxycarbonyl)benzoyl]-β-D-glucopyranuronic Acid; MEHP-Gluc (common abbreviation); Contact for additional synonyms.
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Quality Control

Our Monoethyl Phthalate o-β-D-Glucuronide is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure identity, purity, and stability. Each batch is supplied with a comprehensive Certificate of Analysis (COA) detailing specifications such as assay purity, impurity profile, and confirmation of structure. We support research requiring traceable and reliable reference materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item Specification
Appearance White to off-white solid
Identification (IR) Conforms to structure
Identification (HPLC) Retention time matches reference
Purity (HPLC) ≥95.0%
Water Content (KF) ≤5.0%
Heavy Metals ≤20 ppm
Residual Solvents (GC) Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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