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3-(cis-9-Octadecen-1-Yl)-Sn-Glycero-1-Phosphate (Monosodium Salt) CAS NO 666827-84-5


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CAS No.:666827-84-5

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

3-(cis-9-Octadecen-1-Yl)-Sn-Glycero-1-Phosphate (Monosodium Salt) is a high-purity, synthetic phospholipid derivative, specifically a lysophosphatidic acid (LPA) analogue with an oleoyl chain. This compound is a critical biochemical tool and a key intermediate in lipid research and pharmaceutical development. It is primarily utilized by researchers and manufacturers in the life sciences sector for studying cell signaling pathways, membrane biophysics, and as a precursor for more complex lipid conjugates.

Application

  • Biochemical Research: As a standard or substrate in enzymatic assays and studies of lipid metabolism and signaling, particularly involving lysophosphatidic acid receptors (LPARs).
  • Pharmaceutical Development: Serves as a key intermediate or active pharmaceutical ingredient (API) precursor in the synthesis of novel lipid-based therapeutics and drug delivery systems.
  • Lipidomics & Analytical Standards: Used as a certified reference material (CRM) for mass spectrometry-based lipid identification and quantification in complex biological samples.
  • Cell Culture & Biotechnology: Employed in media formulations to study its effects on cell proliferation, differentiation, and migration in various cell lines.
  • Liposome & Nanoparticle Formulation: Acts as a component for creating specialized lipid bilayers with specific fluidity and surface charge properties for targeted delivery applications.
  • Diagnostic Reagent Manufacturing: Incorporated into diagnostic kits for the detection and study of phospholipase activity or related metabolic disorders.

Basic Information

Product Name 3-(cis-9-Octadecen-1-Yl)-Sn-Glycero-1-Phosphate (Monosodium Salt)
CAS No. 666827-84-5
Molecular Formula C21H42NaO7P
Molecular Weight 460.51 g/mol
Synonyms 1-Oleoyl-2-hydroxy-sn-glycero-3-phosphate (sodium salt); LPA(18:1) sodium salt; Lysophosphatidic acid (18:1) sodium salt; 1-Oleoyl-2-hydroxy-sn-glycero-3-phosphoric acid sodium salt; (2R)-2-Hydroxy-3-(oleoyloxy)propyl dihydrogen phosphate sodium salt; sn-Glycero-1-Phosphate, 3-(cis-9-Octadecen-1-Yl)-, monosodium salt; Oleoyl-LPA sodium salt; 1-Oleoyl-LPA (sodium)
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Quality Control

Our 3-(cis-9-Octadecen-1-Yl)-Sn-Glycero-1-Phosphate (Monosodium Salt) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical and isomeric purity and identity confirmation. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, supporting compliance with research and cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant. This product is hygroscopic (moisture-sensitive). For long-term storage, keep under an inert atmosphere (argon or nitrogen) to prevent oxidation. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item Specification
Appearance White to off-white solid or waxy solid
Identification (HPLC/MS) Conforms to reference standard
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 95% (Area %)
Isomeric Purity (sn-1) ≥ 98%
Water Content (KF) ≤ 2.0 %
Residual Solvents (GC) Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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