Description

Proline, 3,4-Dihydroxy-, (3S,4R)- (9Ci) CAS NO 654083-19-9 is a high-purity, stereochemically defined derivative of the amino acid proline, featuring two hydroxyl groups on its pyrrolidine ring. This specific configuration is critical for its role as a key chiral building block and intermediate in advanced organic synthesis. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and fine chemical industries. The compound's unique structure makes it valuable for developing novel active pharmaceutical ingredients (APIs) and complex bioactive molecules.

Application

• Pharmaceutical Intermediate: Serves as a crucial chiral synthon for the synthesis of complex drug candidates, particularly in protease inhibitor and neurological drug research.
• Biochemical Research: Used as a standard or reagent in enzymatic studies and metabolic pathway investigations due to its modified amino acid structure.
• Peptide Synthesis: Incorporated into custom peptides to introduce conformational constraints and enhance biological activity or stability.
• Asymmetric Catalysis: Employed as a precursor for ligands or organocatalysts used in stereoselective chemical transformations.
• Fine Chemical Production: Acts as a building block for the manufacture of specialty chemicals, agrochemicals, and advanced materials.
• Reference Standard: Utilized as a high-purity analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	Proline, 3,4-Dihydroxy-, (3S,4R)- (9Ci)
CAS No.	654083-19-9
Molecular Formula	C5H9NO3
Molecular Weight	131.13 g/mol
Synonyms	(3S,4R)-3,4-Dihydroxy-L-proline; L-3,4-Dihydroxyproline; (2S,3R,4R)-3,4-Dihydroxypyrrolidine-2-carboxylic Acid; 3,4-Dihydroxy-L-proline; cis-3,4-Dihydroxy-L-proline; 654083-19-9; (3S,4R)-3,4-Dihydroxypyrrolidine-2-carboxylic Acid
EINECS	Contact for details

Quality Control

Our Proline, 3,4-Dihydroxy-, (3S,4R)- (9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (3S,4R)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.