Description

Cyclopropanemethanamine, 2-(2-Ethyl-7-Benzoxazolyl)-, (1R,2R)- (9Ci) CAS NO 625851-09-4 is a chiral, optically active benzoxazole derivative featuring a cyclopropane moiety, serving as a sophisticated pharmaceutical intermediate and research chemical. Its unique stereochemistry and molecular architecture make it a valuable building block for the synthesis of novel bioactive compounds. This high-purity intermediate is primarily targeted at pharmaceutical R&D and fine chemical synthesis sectors, where precise molecular control is paramount.

Application

This specialized chiral amine is utilized in advanced chemical synthesis across several high-value industries:

• Pharmaceutical Intermediate: A key chiral precursor in the research and development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and antiviral targets.
• Asymmetric Synthesis: Employed as a chiral auxiliary or building block in stereoselective synthesis to create enantiomerically pure compounds.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and library synthesis for drug discovery programs.
• Ligand and Catalyst Development: Serves as a scaffold for developing novel ligands in catalytic asymmetric reactions.
• Fine Chemical Production: Incorporated into the synthesis of complex, high-value specialty chemicals and agrochemicals.

Basic Information

Item	Detail
Product Name	Cyclopropanemethanamine, 2-(2-Ethyl-7-Benzoxazolyl)-, (1R,2R)- (9Ci)
CAS No.	625851-09-4
Molecular Formula	C15H18N2O
Molecular Weight	242.32 g/mol
Synonyms	(1R,2R)-2-(2-Ethyl-1,3-benzoxazol-7-yl)cyclopropanemethanamine; (1R,2R)-2-(2-Ethylbenzoxazol-7-yl)cyclopropylmethylamine; (1R,2R)-2-(2-Ethyl-7-benzoxazolyl)cyclopropanemethylamine; (1R,2R)-rel-2-(2-Ethyl-7-benzoxazolyl)cyclopropanemethanamine; 7-[(1R,2R)-2-(Aminomethyl)cyclopropyl]-2-ethyl-1,3-benzoxazole
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality protocols to ensure batch-to-batch consistency and high enantiomeric purity. Quality is verified through comprehensive analytical techniques including HPLC, chiral chromatography, GC, and NMR. A Certificate of Analysis (COA) detailing identity, purity, chiral excess, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). This compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.