Description

Bis-Tos-(2-Hydroxyethyl Disulfide) is a specialized organosulfur compound with a disulfide linkage protected by tosylate groups. This chemical is valued for its role as a versatile intermediate and protecting group reagent in sophisticated organic synthesis. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for developing novel compounds and active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing disulfide or thiol functionalities.
• Peptide Chemistry: Used as a protecting group reagent for thiols in solid-phase and solution-phase peptide synthesis.
• Bioconjugation & Linker Chemistry: Serves as a cleavable linker or cross-linking agent in the development of antibody-drug conjugates (ADCs) and other bioconjugates.
• Agrochemical Synthesis: Employed in the research and production of novel herbicides, fungicides, and insecticides.
• Material Science Research: Investigated for use in creating functional polymers and self-assembled monolayers (SAMs) with specific surface properties.
• Chemical Biology Probes: Utilized in the design and synthesis of probes for studying redox biology and protein function.

Basic Information

Product Name	Bis-Tos-(2-Hydroxyethyl Disulfide)
CAS No.	69981-39-1
Molecular Formula	C₁₈H₂₂O₆S₄
Molecular Weight	470.62 g/mol
Synonyms	2,2'-Disulfanediylbis(ethyl 4-methylbenzenesulfonate); 1,2-Bis(2-((4-methylphenyl)sulfonyloxy)ethyl)disulfane; Bis(2-((tosyloxy)ethyl)) disulfide; 2-Hydroxyethyl disulfide ditosylate; Bis-Tos-HEDS; DTED; Ethanol, 2,2'-dithiobis-, 1,1'-ditosylate
EINECS	Contact for details

Quality Control

Our Bis-Tos-(2-Hydroxyethyl Disulfide) is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR, and residual solvent analysis, to ensure it meets the high standards required for research and production. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.