Description

Gaba Permease CAS NO 69913-01-5 is a specialized chemical compound designed for advanced biochemical and pharmaceutical research. This compound is critical for studies involving the modulation of GABA (γ-aminobutyric acid) transport and receptor systems, which are fundamental to neurological function. It serves as a key research tool for neuroscientists, pharmacologists, and medicinal chemists developing next-generation neuroactive agents and therapeutic interventions.

Application

• Neuroscience Research: Used as a potent tool compound for investigating GABAergic neurotransmission, synaptic plasticity, and neuronal excitability.
• Drug Discovery & Development: Serves as a reference standard and pharmacological probe in high-throughput screening (HTS) campaigns targeting GABA transporters (GATs) for conditions like epilepsy, anxiety, and chronic pain.
• Biochemical Assays: Employed in in vitro studies to characterize the kinetics and inhibition profiles of GABA permease and related membrane transport proteins.
• Medicinal Chemistry: Acts as a crucial intermediate or building block for the synthesis of novel neuropharmaceuticals with enhanced blood-brain barrier permeability.
• Academic & Institutional Research: Supports fundamental research in universities and institutes focused on understanding the molecular basis of neurological disorders.

Basic Information

Item	Details
Product Name	Gaba Permease
CAS No.	69913-01-5
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	GABA Permease; GABA Transporter Modulator; 4-Amino-3-phenylbutyric acid derivative; (R)-(-)-3-Phenyl-4-aminobutyric acid permease inhibitor; Nipecotic acid benzyl ester analog; GAT-1 Inhibitor research compound; SKF-89976A related compound; Neurotransmitter uptake inhibitor
EINECS	Contact for details

Quality Control

Our Gaba Permease is manufactured under strict quality control protocols to ensure batch-to-batch consistency and reliability for sensitive research applications. Each lot undergoes comprehensive analytical testing, including purity verification by HPLC and structural confirmation. A Certificate of Analysis (COA) detailing identity, purity, and assay results is provided with every shipment to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture. For long-term storage, consider using a desiccator.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.