Description

Arachidic Acid n-Hydroxysuccinimide Ester is a high-purity, reactive chemical intermediate designed for advanced bioconjugation and labeling applications. This compound is critical for researchers and manufacturers requiring precise, covalent attachment of arachidic acid (C20:0) moieties to amine-containing molecules like proteins, peptides, or amino-modified surfaces. It is primarily utilized in the life sciences sector for developing diagnostic reagents, creating stable lipid-protein conjugates for vaccine research, and functionalizing nanomaterials for targeted drug delivery systems.

Application

• Bioconjugation Reagent: For the covalent coupling of arachidic acid to primary amines on antibodies, enzymes, or other proteins to modify their properties or create immunogens.
• Lipid-Protein Conjugate Synthesis: Essential in vaccine adjuvant research and development for attaching defined lipid chains to carrier proteins.
• Surface Functionalization: Used to introduce long-chain alkyl groups onto amine-coated beads, chips, or nanoparticles for biosensor development or chromatography media.
• Diagnostic Assay Development: Employed in the synthesis of labeled probes and tracers for immunoassays and other diagnostic platforms.
• Polymer Modification: Acts as a reactive monomer or cross-linker for introducing hydrophobic segments into amine-functionalized polymers.
• Biomaterial Engineering: Facilitates the creation of lipidated scaffolds and matrices for tissue engineering and controlled release applications.

Basic Information

Product Name	Arachidic Acid n-Hydroxysuccinimide Ester
CAS No.	69888-87-5
Molecular Formula	C₂₄H₄₁NO₅
Molecular Weight	423.59 g/mol
Synonyms	NHS-Arachidate; Arachidic Acid NHS Ester; Eicosanoic Acid N-Hydroxysuccinimide Ester; N-Succinimidyl Eicosanoate; 20:0 NHS Ester; N-Hydroxysuccinimidyl Arachidate; Eicosanoic Acid, 2,5-Dioxo-1-pyrrolidinyl Ester; Arachidyl-NHS
EINECS	Contact for details

Quality Control

Our Arachidic Acid n-Hydroxysuccinimide Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for sensitive life science applications. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant (e.g., in a sealed bag with silica gel) to minimize hydrolysis. For long-term storage, keep under an inert atmosphere (argon or nitrogen). Allow the sealed vial to equilibrate to room temperature before opening to prevent condensation and moisture ingress.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Water Content (KF)	≤ 1.0 %
Solubility	Soluble in DMF, DMSO, acetonitrile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.