Description

Succinimidyl Myristate CAS NO 69888-86-4 is a high-purity, activated ester derivative of myristic acid, specifically designed for efficient bioconjugation and peptide synthesis. This compound serves as a critical reagent for introducing the myristoyl group into target molecules, a key modification for studying protein lipidation, membrane anchoring, and signal transduction pathways. It is an essential tool for researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors who require reliable and high-quality intermediates for advanced biochemical applications.

Application

• Peptide Synthesis: As an activated ester for the site-specific incorporation of myristic acid into synthetic peptides.
• Protein Labeling & Modification: For the N-terminal myristoylation of proteins to study membrane association, trafficking, and function.
• Bioconjugation & Probe Development: Used to create myristoylated fluorescent probes, affinity tags, or other diagnostic reagents.
• Lipidated Drug Candidate Synthesis: A key building block in the research and development of lipid-conjugated therapeutic agents.
• Biochemical Research: Essential for investigating the role of protein myristoylation in cellular processes and disease mechanisms.
• Cross-linking Agent: Can function as a homobifunctional cross-linker for attaching molecules via amine groups.

Basic Information

Product Name	Succinimidyl Myristate
CAS No.	69888-86-4
Molecular Formula	C18H31NO4
Molecular Weight	325.45 g/mol
Synonyms	Myristic Acid N-Hydroxysuccinimide Ester; N-Myristoyloxysuccinimide; NHS-Myristate; Tetradecanoic Acid 2,5-Dioxopyrrolidin-1-yl Ester; 1-[(Tetradecanoyl)oxy]-2,5-pyrrolidinedione; N-Succinimidyl Tetradecanoate; Myristoyl NHS Ester
EINECS	Contact for details

Quality Control

Every batch of Succinimidyl Myristate is manufactured and tested under strict quality management protocols to ensure consistency and high purity suitable for sensitive research and development applications. Our products undergo rigorous quality testing, including HPLC and NMR analysis, to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a freezer at -20°C or below. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to prevent hydrolysis and maintain reactivity. Allow the sealed container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Solubility	Soluble in DMF, DMSO, acetonitrile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.