Description

8-Deoxoannotinine is a specialized diterpenoid alkaloid derivative, a compound of significant interest in advanced organic synthesis and pharmaceutical research. Its unique structural framework makes it a valuable intermediate for developing novel bioactive molecules and exploring complex natural product chemistry. This high-purity compound is primarily utilized by research institutions and pharmaceutical development teams focused on medicinal chemistry, process development, and the synthesis of new chemical entities.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of complex alkaloid-based drug candidates and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a reference standard or precursor in structure-activity relationship (SAR) studies to develop new therapeutic agents.
• Natural Product Synthesis: Acts as a crucial intermediate in the total synthesis or semi-synthesis of diterpenoid alkaloids and related natural products.
• Biochemical Research: Employed in studies investigating the biological activity and mechanism of action of diterpenoid compounds.
• Process Development & Scale-up: Used in optimizing synthetic routes and developing scalable manufacturing processes for advanced intermediates.
• Academic Research: A valuable compound for university laboratories and research institutes studying organic synthesis methodologies and natural product chemistry.

Basic Information

Product Name	8-Deoxoannotinine
CAS No.	69796-60-7
Molecular Formula	C22H33NO4
Molecular Weight	375.51 g/mol
Synonyms	8-Deoxo-annotinine; Delnudine; 13β,14β-Dihydroxyhetisan-2-one, 8,17-epoxy-6,16-cyclo- (and other stereochemical descriptors); Hetisan-2-one, 8,17-epoxy-6,16-cyclo-13,14-dihydroxy- (8R,13R,14R,16R)-; Aconitane diterpenoid alkaloid derivative
EINECS	Contact for details

Quality Control

Our 8-Deoxoannotinine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity assessment and spectroscopic methods (NMR, MS) for structural confirmation. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting the specific results for your quality assurance records.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. For long-term storage, consider storing under inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.