Description

Biotin Tosylate is a chemically modified derivative of the essential vitamin biotin (Vitamin B7), designed to enhance its stability and reactivity for advanced synthesis. This specialized intermediate is critical for creating biotinylated compounds used in research, diagnostics, and targeted drug delivery systems. It is primarily utilized by pharmaceutical R&D teams, diagnostic kit manufacturers, and biotechnology companies developing novel bioconjugates and probes.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing biotin-conjugated active pharmaceutical ingredients (APIs) and prodrugs.
• Diagnostic Reagents: Used to produce biotinylated antibodies, antigens, and nucleotides for ELISA, lateral flow assays, and other immunoassays.
• Bioconjugation & Probes: Facilitates the attachment of biotin to proteins, peptides, and other molecules for avidin/streptavidin-based detection and purification systems.
• Research & Development: Serves as a crucial reagent in academic and industrial labs for studying biomolecular interactions and cellular processes.
• Targeted Drug Delivery: Enables the development of biotin-labeled nanocarriers and ligands for site-specific therapeutic delivery.

Basic Information

Product Name	Biotin Tosylate
CAS No.	69705-14-2
Molecular Formula	C17H22N2O5S
Molecular Weight	366.43 g/mol
Synonyms	Biotin p-toluenesulfonate; Biotin tosylate salt; Vitamin B7 tosylate; D-Biotin p-toluenesulfonate; (+)-Biotin p-toluenesulfonate; Biotin tosylate ester; 5-[(3aS,4S,6aR)-2-Oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentyl 4-methylbenzenesulfonate
EINECS	Contact for details

Quality Control

Our Biotin Tosylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and related substances. Certificates of Analysis (COA) are provided with every shipment to ensure traceability and compliance with your project specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.