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1-Myristoyl-2-Palmitoyl-Sn-Glycero-3-Phosphocholine CAS NO 69525-80-0


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CAS No.:69525-80-0

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

1-Myristoyl-2-Palmitoyl-Sn-Glycero-3-Phosphocholine is a high-purity, synthetic phospholipid with a defined fatty acid chain composition. This compound is a critical component for constructing biomimetic membranes and liposomal delivery systems, offering superior batch-to-batch consistency for research and formulation. It is essential for scientists and manufacturers in the pharmaceutical, biotechnology, and advanced materials sectors who require precise lipid building blocks for drug delivery, diagnostic assays, and membrane biophysics studies.

Application

  • Liposome & Lipid Nanoparticle (LNP) Formulation: A key structural lipid for creating stable, uniform vesicles for drug and gene delivery applications.
  • Biomembrane Research: Used to create model membrane systems (e.g., supported lipid bilayers, vesicles) for studying protein-lipid interactions, membrane permeability, and cell signaling.
  • Diagnostic Reagent Development: Serves as a component in diagnostic kits and assays that utilize liposome-based signal amplification or cell membrane mimics.
  • Excipient in Advanced Formulations: Employed as a functional excipient in topical, parenteral, and inhalable pharmaceutical products to enhance stability and bioavailability.
  • Cosmetic Actives Delivery: Used in high-end cosmetic formulations to encapsulate and improve the skin penetration of active ingredients.
  • Reference Standard: Acts as a certified reference material (CRM) for analytical method development and quality control in lipidomics and related fields.

Basic Information

Product Name 1-Myristoyl-2-Palmitoyl-Sn-Glycero-3-Phosphocholine
CAS No. 69525-80-0
Molecular Formula C39H78NO8P
Molecular Weight 720.01 g/mol
Synonyms MPPC; 14:0-16:0 PC; 1-Myristoyl-2-palmitoyl-sn-glycero-3-phosphocholine; Phosphatidylcholine(14:0/16:0); PC(14:0/16:0); 1-Tetradecanoyl-2-hexadecanoyl-sn-glycero-3-phosphocholine; 3-sn-Phosphatidylcholine, 1-tetradecanoyl-2-hexadecanoyl-; Lyso PC(14:0/0:0) Precursor
EINECS Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry to confirm identity, purity, and fatty acid composition. Certificates of Analysis (COA) with detailed chromatograms and spectral data are available upon request. We adhere to cGMP guidelines for the production of materials intended for pharmaceutical research and development.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation and hydrolysis. This material is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item Specification
Appearance White to off-white solid or waxy solid
Identification (HPLC/MS) Conforms to reference standard
Identification (NMR) Conforms to structure
Assay (HPLC) ≥ 98.0% (Area Percent)
Solvent Content (Residual Solvents) Meets ICH guidelines
Fatty Acid Composition (GC) Myristic Acid (C14:0): 45-55%; Palmitic Acid (C16:0): 45-55%
Water Content (KF) ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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